Instrumentation choice and early radiographic outcome following lateral lumbar interbody fusion (LLIF): Lateral instrumentation versus posterior pedicle screw fixation

Background: Lateral lumbar interbody fusion (LLIF) is a minimally invasive fusion procedure that may be performed with or without supplemental instrumentation. However, there is a paucity of evidence on the effect of supplemental instrumentation technique on perioperative morbidity and fusion rate i...

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Main Authors: Sarah Nuss, Owen P. Leary, Bryan Zheng, Spencer C. Darveau, Adriel Barrios-Anderson, Tianyi Niu, Ziya L. Gokaslan, Prakash Sampath, Albert E. Telfeian, Adetokunbo A. Oyelese, Jared S. Fridley
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:North American Spine Society Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666548422000798
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author Sarah Nuss
Owen P. Leary
Bryan Zheng
Spencer C. Darveau
Adriel Barrios-Anderson
Tianyi Niu
Ziya L. Gokaslan
Prakash Sampath
Albert E. Telfeian
Adetokunbo A. Oyelese
Jared S. Fridley
author_facet Sarah Nuss
Owen P. Leary
Bryan Zheng
Spencer C. Darveau
Adriel Barrios-Anderson
Tianyi Niu
Ziya L. Gokaslan
Prakash Sampath
Albert E. Telfeian
Adetokunbo A. Oyelese
Jared S. Fridley
author_sort Sarah Nuss
collection DOAJ
description Background: Lateral lumbar interbody fusion (LLIF) is a minimally invasive fusion procedure that may be performed with or without supplemental instrumentation. However, there is a paucity of evidence on the effect of supplemental instrumentation technique on perioperative morbidity and fusion rate in LLIF. Methods: A single-institutional retrospective review of patients who underwent LLIF for lumbar spondylosis was conducted. Patients were grouped according to supplemental instrumentation technique: stand-alone LLIF, LLIF with laterally placed instrumentation, or LLIF with posterior percutaneous pedicle screw fixation (PPSF). Outcomes included fusion rates, peri-operative complication, and reoperation; estimated blood loss (EBL); surgery duration; length of stay; and length of follow-up. Results: 82 patients underwent LLIF at 114 levels. 35 patients (42.7%) received supplemental lateral instrumentation, 30 (36.6%) received supplemental PPSF, and 17 (20.7%) underwent stand-alone LLIF. More patients in the lateral instrumentation group had prior lumbar fusion at adjacent levels (23/35, 65.71%) versus stand-alone (3/17, 17.6%) or PPSF (2/30, 6.67%) groups (p = 0.003). 4/17 patients (23.5%) with stand-alone LLIF and 4/35 patients (11.42%) with lateral instrumentation underwent reoperation, versus 0/30 with PPSF (p = 0.030). There was no difference in fusion rates between groups (p = 0.717). Operation duration was longer in patients with PPSF (p < 0.005) and length of follow-up was longer for PPSF than lateral instrumentation (p = 0.001). Choice of instrumentation group was a statistically significant predictor of reoperation. Conclusions: While rates of complete radiographic fusion on imaging follow-up didn't differ, patients receiving PPSF were less likely than stand-alone or lateral instrumentation groups to require reoperation, though operative time was significantly longer. Further study of choice of supplemental instrumentation with LLIF is indicated.
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spelling doaj.art-16a26816f9384d839527acf05c608d9f2022-12-22T04:41:59ZengElsevierNorth American Spine Society Journal2666-54842022-12-0112100176Instrumentation choice and early radiographic outcome following lateral lumbar interbody fusion (LLIF): Lateral instrumentation versus posterior pedicle screw fixationSarah Nuss0Owen P. Leary1Bryan Zheng2Spencer C. Darveau3Adriel Barrios-Anderson4Tianyi Niu5Ziya L. Gokaslan6Prakash Sampath7Albert E. Telfeian8Adetokunbo A. Oyelese9Jared S. Fridley10Department of Neurosurgery, Warren Alpert Medical School of Brown University, Providence, RI 02906Department of Neurosurgery, Warren Alpert Medical School of Brown University, Providence, RI 02906Department of Neurosurgery, Warren Alpert Medical School of Brown University, Providence, RI 02906Department of Neurosurgery, Warren Alpert Medical School of Brown University, Providence, RI 02906Department of Neurosurgery, Warren Alpert Medical School of Brown University, Providence, RI 02906Department of Neurosurgery, Warren Alpert Medical School of Brown University, Providence, RI 02906Department of Neurosurgery, Warren Alpert Medical School of Brown University, Providence, RI 02906Department of Neurosurgery, Warren Alpert Medical School of Brown University, Providence, RI 02906Department of Neurosurgery, Warren Alpert Medical School of Brown University, Providence, RI 02906Department of Neurosurgery, Warren Alpert Medical School of Brown University, Providence, RI 02906Corresponding author at: Dept. of Neurosurgery, Warren Alpert Medical School of Brown University, Rhode Island Hospital, APC 6, 593 Eddy St, Providence, RI 02903.; Department of Neurosurgery, Warren Alpert Medical School of Brown University, Providence, RI 02906Background: Lateral lumbar interbody fusion (LLIF) is a minimally invasive fusion procedure that may be performed with or without supplemental instrumentation. However, there is a paucity of evidence on the effect of supplemental instrumentation technique on perioperative morbidity and fusion rate in LLIF. Methods: A single-institutional retrospective review of patients who underwent LLIF for lumbar spondylosis was conducted. Patients were grouped according to supplemental instrumentation technique: stand-alone LLIF, LLIF with laterally placed instrumentation, or LLIF with posterior percutaneous pedicle screw fixation (PPSF). Outcomes included fusion rates, peri-operative complication, and reoperation; estimated blood loss (EBL); surgery duration; length of stay; and length of follow-up. Results: 82 patients underwent LLIF at 114 levels. 35 patients (42.7%) received supplemental lateral instrumentation, 30 (36.6%) received supplemental PPSF, and 17 (20.7%) underwent stand-alone LLIF. More patients in the lateral instrumentation group had prior lumbar fusion at adjacent levels (23/35, 65.71%) versus stand-alone (3/17, 17.6%) or PPSF (2/30, 6.67%) groups (p = 0.003). 4/17 patients (23.5%) with stand-alone LLIF and 4/35 patients (11.42%) with lateral instrumentation underwent reoperation, versus 0/30 with PPSF (p = 0.030). There was no difference in fusion rates between groups (p = 0.717). Operation duration was longer in patients with PPSF (p < 0.005) and length of follow-up was longer for PPSF than lateral instrumentation (p = 0.001). Choice of instrumentation group was a statistically significant predictor of reoperation. Conclusions: While rates of complete radiographic fusion on imaging follow-up didn't differ, patients receiving PPSF were less likely than stand-alone or lateral instrumentation groups to require reoperation, though operative time was significantly longer. Further study of choice of supplemental instrumentation with LLIF is indicated.http://www.sciencedirect.com/science/article/pii/S2666548422000798Lumbar SpineLateral lumbar interbody fusionLLIFMinimally invasive spine surgerySpinal instrumentation
spellingShingle Sarah Nuss
Owen P. Leary
Bryan Zheng
Spencer C. Darveau
Adriel Barrios-Anderson
Tianyi Niu
Ziya L. Gokaslan
Prakash Sampath
Albert E. Telfeian
Adetokunbo A. Oyelese
Jared S. Fridley
Instrumentation choice and early radiographic outcome following lateral lumbar interbody fusion (LLIF): Lateral instrumentation versus posterior pedicle screw fixation
North American Spine Society Journal
Lumbar Spine
Lateral lumbar interbody fusion
LLIF
Minimally invasive spine surgery
Spinal instrumentation
title Instrumentation choice and early radiographic outcome following lateral lumbar interbody fusion (LLIF): Lateral instrumentation versus posterior pedicle screw fixation
title_full Instrumentation choice and early radiographic outcome following lateral lumbar interbody fusion (LLIF): Lateral instrumentation versus posterior pedicle screw fixation
title_fullStr Instrumentation choice and early radiographic outcome following lateral lumbar interbody fusion (LLIF): Lateral instrumentation versus posterior pedicle screw fixation
title_full_unstemmed Instrumentation choice and early radiographic outcome following lateral lumbar interbody fusion (LLIF): Lateral instrumentation versus posterior pedicle screw fixation
title_short Instrumentation choice and early radiographic outcome following lateral lumbar interbody fusion (LLIF): Lateral instrumentation versus posterior pedicle screw fixation
title_sort instrumentation choice and early radiographic outcome following lateral lumbar interbody fusion llif lateral instrumentation versus posterior pedicle screw fixation
topic Lumbar Spine
Lateral lumbar interbody fusion
LLIF
Minimally invasive spine surgery
Spinal instrumentation
url http://www.sciencedirect.com/science/article/pii/S2666548422000798
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