Extracorporeal Removal of Thermosensitive Liposomal Doxorubicin from Systemic Circulation after Tumor Delivery to Reduce Toxicities

Extracorporeal Removal of Thermosensitive Liposomal Doxorubicin from Systemic Circulation after Tumor Delivery to Reduce Toxicities

Thermosensitive liposomal doxorubicin (TSL-Dox) combined with localized hyperthermia enables targeted drug delivery. Tumor drug uptake occurs only during hyperthermia. We developed a novel method for removal of systemic TSL-Dox remaining after hyperthermia-triggered delivery to reduce toxicities. Th...

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Bibliographic Details
Main Authors: Anjan Motamarry, A. Marissa Wolfe, Krishna K. Ramajayam, Sanket Pattanaik, Thomas Benton, Yuri Peterson, Pegah Faridi, Punit Prakash, Katherine Twombley, Dieter Haemmerich
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
thermosensitive liposomes
hyperthermia
extracorporeal circulation
Online Access:https://www.mdpi.com/2072-6694/14/5/1322

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