Gouty Arthropathy: Review of Clinical Manifestations and Treatment, with Emphasis on Imaging
Gout, a crystalline arthropathy caused by the deposition of monosodium urate crystals in the articular and periarticular soft tissues, is a frequent cause of painful arthropathy. Imaging has an important role in the initial evaluation as well as the treatment and follow up of gouty arthropathy. The...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-12-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/1/166 |
| _version_ | 1797498582996090880 |
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| author | Jennifer S. Weaver Ernest R. Vina Peter L. Munk Andrea S. Klauser Jamie M. Elifritz Mihra S. Taljanovic |
| author_facet | Jennifer S. Weaver Ernest R. Vina Peter L. Munk Andrea S. Klauser Jamie M. Elifritz Mihra S. Taljanovic |
| author_sort | Jennifer S. Weaver |
| collection | DOAJ |
| description | Gout, a crystalline arthropathy caused by the deposition of monosodium urate crystals in the articular and periarticular soft tissues, is a frequent cause of painful arthropathy. Imaging has an important role in the initial evaluation as well as the treatment and follow up of gouty arthropathy. The imaging findings of gouty arthropathy on radiography, ultrasonography, computed tomography, dual energy computed tomography, and magnetic resonance imaging are described to include findings of the early, acute and chronic phases of gout. These findings include early monosodium urate deposits, osseous erosions, and tophi, which may involve periarticular tissues, tendons, and bursae. Treatment of gout includes non-steroidal anti-inflammatories, colchicine, glucocorticoids, interleukin-1 inhibitors, xanthine oxidase inhibitors, uricosuric drugs, and recombinant uricase. Imaging is critical in monitoring response to therapy; clinical management can be modulated based on imaging findings. This review article describes the current standard of care in imaging and treatment of gouty arthropathy. |
| first_indexed | 2024-03-10T03:35:24Z |
| format | Article |
| id | doaj.art-16a6e429d19544069673badcf6c535dc |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T03:35:24Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-16a6e429d19544069673badcf6c535dc2023-11-23T11:44:38ZengMDPI AGJournal of Clinical Medicine2077-03832021-12-0111116610.3390/jcm11010166Gouty Arthropathy: Review of Clinical Manifestations and Treatment, with Emphasis on ImagingJennifer S. Weaver0Ernest R. Vina1Peter L. Munk2Andrea S. Klauser3Jamie M. Elifritz4Mihra S. Taljanovic5Department of Radiology, University of New Mexico, Albuquerque, NM 87131, USADepartment of Medicine, University of Arizona Arthritis Center, Tucson, AZ 85724, USADepartment of Radiology, University of British Columbia, Vancouver, BC V6T 1Z4, CanadaRadiology Department, Medical University Innsbruck, Anichstrasse 35, 6020 Innsbruck, AustriaDepartments of Radiology and Pathology, University of New Mexico, Albuquerque, NM 87131, USADepartment of Radiology, University of New Mexico, Albuquerque, NM 87131, USAGout, a crystalline arthropathy caused by the deposition of monosodium urate crystals in the articular and periarticular soft tissues, is a frequent cause of painful arthropathy. Imaging has an important role in the initial evaluation as well as the treatment and follow up of gouty arthropathy. The imaging findings of gouty arthropathy on radiography, ultrasonography, computed tomography, dual energy computed tomography, and magnetic resonance imaging are described to include findings of the early, acute and chronic phases of gout. These findings include early monosodium urate deposits, osseous erosions, and tophi, which may involve periarticular tissues, tendons, and bursae. Treatment of gout includes non-steroidal anti-inflammatories, colchicine, glucocorticoids, interleukin-1 inhibitors, xanthine oxidase inhibitors, uricosuric drugs, and recombinant uricase. Imaging is critical in monitoring response to therapy; clinical management can be modulated based on imaging findings. This review article describes the current standard of care in imaging and treatment of gouty arthropathy.https://www.mdpi.com/2077-0383/11/1/166goutmonosodium urate crystalscrystalline arthropathyimagingmagnetic resonance imagingsonography |
| spellingShingle | Jennifer S. Weaver Ernest R. Vina Peter L. Munk Andrea S. Klauser Jamie M. Elifritz Mihra S. Taljanovic Gouty Arthropathy: Review of Clinical Manifestations and Treatment, with Emphasis on Imaging Journal of Clinical Medicine gout monosodium urate crystals crystalline arthropathy imaging magnetic resonance imaging sonography |
| title | Gouty Arthropathy: Review of Clinical Manifestations and Treatment, with Emphasis on Imaging |
| title_full | Gouty Arthropathy: Review of Clinical Manifestations and Treatment, with Emphasis on Imaging |
| title_fullStr | Gouty Arthropathy: Review of Clinical Manifestations and Treatment, with Emphasis on Imaging |
| title_full_unstemmed | Gouty Arthropathy: Review of Clinical Manifestations and Treatment, with Emphasis on Imaging |
| title_short | Gouty Arthropathy: Review of Clinical Manifestations and Treatment, with Emphasis on Imaging |
| title_sort | gouty arthropathy review of clinical manifestations and treatment with emphasis on imaging |
| topic | gout monosodium urate crystals crystalline arthropathy imaging magnetic resonance imaging sonography |
| url | https://www.mdpi.com/2077-0383/11/1/166 |
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