The synthetic phospholipid C8-C1P determines pro-angiogenic and pro-reparative features in human macrophages restraining the proinflammatory M1-like phenotype

The synthetic phospholipid C8-C1P determines pro-angiogenic and pro-reparative features in human macrophages restraining the proinflammatory M1-like phenotype

Monocytes (Mo) are highly plastic myeloid cells that differentiate into macrophages after extravasation, playing a pivotal role in the resolution of inflammation and regeneration of injured tissues. Wound-infiltrated monocytes/macrophages are more pro-inflammatory at early time points, while showing...

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Bibliographic Details
Main Authors: Juan Manuel Ortiz Wilczyñski, Hebe Agustina Mena, Martin Manuel Ledesma, Cinthia Mariel Olexen, Enrique Podaza, Mirta Schattner, Soledad Negrotto, Andrea Emilse Errasti, Eugenio Antonio Carrera Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
ceramide 1-phosphate
macrophages
inflammation
tissue repair
angiogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1162671/full

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