The RNA methyltransferase METTL16 enhances cholangiocarcinoma growth through PRDM15-mediated FGFR4 expression

The RNA methyltransferase METTL16 enhances cholangiocarcinoma growth through PRDM15-mediated FGFR4 expression

Abstract Background RNA N6-Methyladenosine (m6A) modification is implicated in the progression of human cancers including cholangiocarcinoma (CCA). METTL16 is recently identified as a new RNA methyltransferase responsible for m6A modification, although the role of METTL16 in CCA has not yet been exa...

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Bibliographic Details
Main Authors: Nianli Liu, Jinqiang Zhang, Weina Chen, Wenbo Ma, Tong Wu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Cholangiocarcinoma
METTL16
PRDM15
FGFR4
m6A modification
Online Access:https://doi.org/10.1186/s13046-023-02844-5

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