The Interaction of Mandarin Fish DDX41 with STING Evokes type I Interferon Responses Inhibiting Ranavirus Replication

The Interaction of Mandarin Fish DDX41 with STING Evokes type I Interferon Responses Inhibiting Ranavirus Replication

DDX41 is an intracellular DNA sensor that evokes type I interferon (IFN-I) production via the adaptor stimulator of interferon gene (STING), triggering innate immune responses against viral infection. However, the regulatory mechanism of the DDX41-STING pathway in teleost fish remains unclear. The m...

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Bibliographic Details
Main Authors: Xiao-Wei Qin, Zhi-Yong Luo, Wei-Qiang Pan, Jian He, Zhi-Min Li, Yang Yu, Chang Liu, Shao-Ping Weng, Jian-Guo He, Chang-Jun Guo
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Viruses
Subjects:
DDX41
STING
ranavirus
interferon
innate immune
mandarin fish
Online Access:https://www.mdpi.com/1999-4915/15/1/58

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