satisfaction
Objective To analyze the adverse drug reaction（ADR） reports of hydroxychloroquine for clinical medication safety. Methods The ADR reports of hydroxychloroquine between May 2019 and May 2021 were analyzed. Age, reasons for drug use, time of ADR, combined drug use, and ADR outcomes were statistically...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
2022-05-01
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| Series: | 口腔疾病防治 |
| Subjects: | |
| Online Access: | http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2022.05.007 |
| _version_ | 1818323221023293440 |
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| author | LIN Yao HUANG Jing XUE Xiaojuan ZHANG Huan FENG Bin |
| author_facet | LIN Yao HUANG Jing XUE Xiaojuan ZHANG Huan FENG Bin |
| author_sort | LIN Yao |
| collection | DOAJ |
| description | Objective To analyze the adverse drug reaction（ADR） reports of hydroxychloroquine for clinical medication safety. Methods The ADR reports of hydroxychloroquine between May 2019 and May 2021 were analyzed. Age, reasons for drug use, time of ADR, combined drug use, and ADR outcomes were statistically analyzed. Results No severe ADR was reported. Patients over 60 years old accounted for 53.85% of the total cases, and the time of ADR appearance was significantly earlier among those under 60 years old. A total of 61.54% of ADRs were involved in multiple organs, and optic neurotoxicity was reported in 46.15% of cases. Conclusion In the treatment of oral lichen planus with hydroxychloroquine, adverse drug reactions should be monitored, and increased attention should be given to patients over 60 years old to ensure the safety of this medication. |
| first_indexed | 2024-12-13T11:09:14Z |
| format | Article |
| id | doaj.art-16b1ff3ee1144e1cba567db1b945bcf6 |
| institution | Directory Open Access Journal |
| issn | 2096-1456 |
| language | zho |
| last_indexed | 2024-12-13T11:09:14Z |
| publishDate | 2022-05-01 |
| publisher | Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases |
| record_format | Article |
| series | 口腔疾病防治 |
| spelling | doaj.art-16b1ff3ee1144e1cba567db1b945bcf62022-12-21T23:48:48ZzhoEditorial Department of Journal of Prevention and Treatment for Stomatological Diseases口腔疾病防治2096-14562022-05-0130535035410.12016/j.issn.2096-1456.2022.05.007satisfactionLIN Yao0 HUANG Jing1XUE Xiaojuan2ZHANG Huan3FENG Bin4State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Pharmacy, School of Stomatology, the Fourth Military Medical UniversityState Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Pharmacy, School of Stomatology, the Fourth Military Medical UniversityState Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Pharmacy, School of Stomatology, the Fourth Military Medical UniversityState Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Pharmacy, School of Stomatology, the Fourth Military Medical UniversityState Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases & Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Pharmacy, School of Stomatology, the Fourth Military Medical UniversityObjective To analyze the adverse drug reaction（ADR） reports of hydroxychloroquine for clinical medication safety. Methods The ADR reports of hydroxychloroquine between May 2019 and May 2021 were analyzed. Age, reasons for drug use, time of ADR, combined drug use, and ADR outcomes were statistically analyzed. Results No severe ADR was reported. Patients over 60 years old accounted for 53.85% of the total cases, and the time of ADR appearance was significantly earlier among those under 60 years old. A total of 61.54% of ADRs were involved in multiple organs, and optic neurotoxicity was reported in 46.15% of cases. Conclusion In the treatment of oral lichen planus with hydroxychloroquine, adverse drug reactions should be monitored, and increased attention should be given to patients over 60 years old to ensure the safety of this medication.http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2022.05.007hydroxychloroquine，oral mucosal disease，adverse-drug reaction，optic neurotoxicity，vision screening，cardiotoxicity，medication safety，package inserts of drug， |
| spellingShingle | LIN Yao HUANG Jing XUE Xiaojuan ZHANG Huan FENG Bin satisfaction 口腔疾病防治 hydroxychloroquine， oral mucosal disease， adverse-drug reaction， optic neurotoxicity， vision screening， cardiotoxicity， medication safety， package inserts of drug， |
| title | satisfaction |
| title_full | satisfaction |
| title_fullStr | satisfaction |
| title_full_unstemmed | satisfaction |
| title_short | satisfaction |
| title_sort | satisfaction |
| topic | hydroxychloroquine， oral mucosal disease， adverse-drug reaction， optic neurotoxicity， vision screening， cardiotoxicity， medication safety， package inserts of drug， |
| url | http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2022.05.007 |
| work_keys_str_mv | AT linyao satisfaction AT huangjing satisfaction AT xuexiaojuan satisfaction AT zhanghuan satisfaction AT fengbin satisfaction |