INTUITION: a data platform to integrate human epilepsy clinical care and support for discovery
To make appropriate clinical decisions, clinicians consider many types of data from multiple sources to arrive at a diagnosis and plan. However, the current health systems have siloed data, making it challenging to develop information platforms that integrate this process into a single place for com...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-06-01
|
| Series: | Frontiers in Digital Health |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fdgth.2023.1091508/full |
| _version_ | 1797808930626207744 |
|---|---|
| author | Biswajit Maharathi Biswajit Maharathi Fozia Mir Karthik Hosur Jeffrey A. Loeb Jeffrey A. Loeb |
| author_facet | Biswajit Maharathi Biswajit Maharathi Fozia Mir Karthik Hosur Jeffrey A. Loeb Jeffrey A. Loeb |
| author_sort | Biswajit Maharathi |
| collection | DOAJ |
| description | To make appropriate clinical decisions, clinicians consider many types of data from multiple sources to arrive at a diagnosis and plan. However, the current health systems have siloed data, making it challenging to develop information platforms that integrate this process into a single place for comprehensive clinical evaluation and research. INTUITION is a human brain integrative data system that facilitates multimodal data integration, unified storage, cohort selection, and analysis of multidisciplinary datasets. In this article, we describe the use of INTUITION to include electronic health records together with co-registered neuroimaging and EEG from patients who undergo invasive brain surgery for epilepsy. In addition to providing clinically useful visualizations and analytics to help guide surgical planning, INTUITION also links a bank of human brain epileptic tissues from specific brain locations to quantitative EEG, imaging, histology, and omics studies in a unique, completely integrated informatics platform. Having a clinically useful platform for integrating multimodal datasets can not only aid in clinical management decisions but also in creating a unique resource for research and discovery when linked to spatially mapped tissue samples. |
| first_indexed | 2024-03-13T06:44:59Z |
| format | Article |
| id | doaj.art-16b2c7bc8be346bbbdd4ebd462114017 |
| institution | Directory Open Access Journal |
| issn | 2673-253X |
| language | English |
| last_indexed | 2024-03-13T06:44:59Z |
| publishDate | 2023-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Digital Health |
| spelling | doaj.art-16b2c7bc8be346bbbdd4ebd4621140172023-06-08T06:27:51ZengFrontiers Media S.A.Frontiers in Digital Health2673-253X2023-06-01510.3389/fdgth.2023.10915081091508INTUITION: a data platform to integrate human epilepsy clinical care and support for discoveryBiswajit Maharathi0Biswajit Maharathi1Fozia Mir2Karthik Hosur3Jeffrey A. Loeb4Jeffrey A. Loeb5Department of Neurology and Rehabilitation, University of Illinois, Chicago, IL, United StatesCenter for Clinical and Translational Science, University of Illinois at Chicago, Chicago, IL, United StatesDepartment of Neurology and Rehabilitation, University of Illinois, Chicago, IL, United StatesDepartment of Neurology and Rehabilitation, University of Illinois, Chicago, IL, United StatesDepartment of Neurology and Rehabilitation, University of Illinois, Chicago, IL, United StatesCenter for Clinical and Translational Science, University of Illinois at Chicago, Chicago, IL, United StatesTo make appropriate clinical decisions, clinicians consider many types of data from multiple sources to arrive at a diagnosis and plan. However, the current health systems have siloed data, making it challenging to develop information platforms that integrate this process into a single place for comprehensive clinical evaluation and research. INTUITION is a human brain integrative data system that facilitates multimodal data integration, unified storage, cohort selection, and analysis of multidisciplinary datasets. In this article, we describe the use of INTUITION to include electronic health records together with co-registered neuroimaging and EEG from patients who undergo invasive brain surgery for epilepsy. In addition to providing clinically useful visualizations and analytics to help guide surgical planning, INTUITION also links a bank of human brain epileptic tissues from specific brain locations to quantitative EEG, imaging, histology, and omics studies in a unique, completely integrated informatics platform. Having a clinically useful platform for integrating multimodal datasets can not only aid in clinical management decisions but also in creating a unique resource for research and discovery when linked to spatially mapped tissue samples.https://www.frontiersin.org/articles/10.3389/fdgth.2023.1091508/fullepilepsysystems biologyintegrated informaticsneurologyintuition |
| spellingShingle | Biswajit Maharathi Biswajit Maharathi Fozia Mir Karthik Hosur Jeffrey A. Loeb Jeffrey A. Loeb INTUITION: a data platform to integrate human epilepsy clinical care and support for discovery Frontiers in Digital Health epilepsy systems biology integrated informatics neurology intuition |
| title | INTUITION: a data platform to integrate human epilepsy clinical care and support for discovery |
| title_full | INTUITION: a data platform to integrate human epilepsy clinical care and support for discovery |
| title_fullStr | INTUITION: a data platform to integrate human epilepsy clinical care and support for discovery |
| title_full_unstemmed | INTUITION: a data platform to integrate human epilepsy clinical care and support for discovery |
| title_short | INTUITION: a data platform to integrate human epilepsy clinical care and support for discovery |
| title_sort | intuition a data platform to integrate human epilepsy clinical care and support for discovery |
| topic | epilepsy systems biology integrated informatics neurology intuition |
| url | https://www.frontiersin.org/articles/10.3389/fdgth.2023.1091508/full |
| work_keys_str_mv | AT biswajitmaharathi intuitionadataplatformtointegratehumanepilepsyclinicalcareandsupportfordiscovery AT biswajitmaharathi intuitionadataplatformtointegratehumanepilepsyclinicalcareandsupportfordiscovery AT foziamir intuitionadataplatformtointegratehumanepilepsyclinicalcareandsupportfordiscovery AT karthikhosur intuitionadataplatformtointegratehumanepilepsyclinicalcareandsupportfordiscovery AT jeffreyaloeb intuitionadataplatformtointegratehumanepilepsyclinicalcareandsupportfordiscovery AT jeffreyaloeb intuitionadataplatformtointegratehumanepilepsyclinicalcareandsupportfordiscovery |