Nevus unius lateris with bilateral oral mucosal lesions: An unusual presentation

Verrucous epidermal nevi (VEN) are cutaneous hamartomas characterized by keratinocytic hyperplasia. Majority are linear in distribution and tend to follow the Blaschko lines; however, some may have zosteriform (segmental) or systematized distribution involving widespread areas of skin. The systemati...

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Main Authors: Lovleen Kaur, Bharat B Mahajan, Mohita Mahajan, Shaminder Singh Dhillon
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Indian Dermatology Online Journal
Subjects:
Online Access:http://www.idoj.in/article.asp?issn=2229-5178;year=2021;volume=12;issue=2;spage=302;epage=306;aulast=Kaur
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author Lovleen Kaur
Bharat B Mahajan
Mohita Mahajan
Shaminder Singh Dhillon
author_facet Lovleen Kaur
Bharat B Mahajan
Mohita Mahajan
Shaminder Singh Dhillon
author_sort Lovleen Kaur
collection DOAJ
description Verrucous epidermal nevi (VEN) are cutaneous hamartomas characterized by keratinocytic hyperplasia. Majority are linear in distribution and tend to follow the Blaschko lines; however, some may have zosteriform (segmental) or systematized distribution involving widespread areas of skin. The systematized ones are further classified into “Nevus Unius Lateris” when one-half of the body is affected, and “Ichthyosis Hystrix” showing bilateral distribution, both being the uncommon forms. Although it can affect any body part, it rarely involves the head and neck region with seldom involvement of mucosae, scalp, and ear lobes. We saw a 6-year-old child with multiple hyperpigmented verrucous plaques predominantly present over left half of the body, ipsilateral alopecia scalp, and verrucous lesions involving mucosae of palate and tongue, which were present bilaterally. Previously, case reports of oral lesions related to VEN had demonstrated segmental, midline, or unilateral distribution. Hereby, we report this peculiar case of Nevus Unius Lateris with bilateral oral mucosal involvement, owing to its rarity.
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spelling doaj.art-16b2d0da59f1488ea749bbfd8ca5e5492022-12-21T18:12:52ZengWolters Kluwer Medknow PublicationsIndian Dermatology Online Journal2229-51782021-01-0112230230610.4103/idoj.IDOJ_454_20Nevus unius lateris with bilateral oral mucosal lesions: An unusual presentationLovleen KaurBharat B MahajanMohita MahajanShaminder Singh DhillonVerrucous epidermal nevi (VEN) are cutaneous hamartomas characterized by keratinocytic hyperplasia. Majority are linear in distribution and tend to follow the Blaschko lines; however, some may have zosteriform (segmental) or systematized distribution involving widespread areas of skin. The systematized ones are further classified into “Nevus Unius Lateris” when one-half of the body is affected, and “Ichthyosis Hystrix” showing bilateral distribution, both being the uncommon forms. Although it can affect any body part, it rarely involves the head and neck region with seldom involvement of mucosae, scalp, and ear lobes. We saw a 6-year-old child with multiple hyperpigmented verrucous plaques predominantly present over left half of the body, ipsilateral alopecia scalp, and verrucous lesions involving mucosae of palate and tongue, which were present bilaterally. Previously, case reports of oral lesions related to VEN had demonstrated segmental, midline, or unilateral distribution. Hereby, we report this peculiar case of Nevus Unius Lateris with bilateral oral mucosal involvement, owing to its rarity.http://www.idoj.in/article.asp?issn=2229-5178;year=2021;volume=12;issue=2;spage=302;epage=306;aulast=Kaurcutaneous mosaicismnevus unius laterisoral epidermal nevusverrucous epidermal nevus
spellingShingle Lovleen Kaur
Bharat B Mahajan
Mohita Mahajan
Shaminder Singh Dhillon
Nevus unius lateris with bilateral oral mucosal lesions: An unusual presentation
Indian Dermatology Online Journal
cutaneous mosaicism
nevus unius lateris
oral epidermal nevus
verrucous epidermal nevus
title Nevus unius lateris with bilateral oral mucosal lesions: An unusual presentation
title_full Nevus unius lateris with bilateral oral mucosal lesions: An unusual presentation
title_fullStr Nevus unius lateris with bilateral oral mucosal lesions: An unusual presentation
title_full_unstemmed Nevus unius lateris with bilateral oral mucosal lesions: An unusual presentation
title_short Nevus unius lateris with bilateral oral mucosal lesions: An unusual presentation
title_sort nevus unius lateris with bilateral oral mucosal lesions an unusual presentation
topic cutaneous mosaicism
nevus unius lateris
oral epidermal nevus
verrucous epidermal nevus
url http://www.idoj.in/article.asp?issn=2229-5178;year=2021;volume=12;issue=2;spage=302;epage=306;aulast=Kaur
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AT bharatbmahajan nevusuniuslateriswithbilateraloralmucosallesionsanunusualpresentation
AT mohitamahajan nevusuniuslateriswithbilateraloralmucosallesionsanunusualpresentation
AT shamindersinghdhillon nevusuniuslateriswithbilateraloralmucosallesionsanunusualpresentation