Efficacy and safety of fenofibrate add-on therapy in patients with primary biliary cholangitis refractory to ursodeoxycholic acid: A retrospective study and updated meta-analysis

Efficacy and safety of fenofibrate add-on therapy in patients with primary biliary cholangitis refractory to ursodeoxycholic acid: A retrospective study and updated meta-analysis

Background: Ursodeoxycholic acid (UDCA) is currently used for the treatment of primary biliary cholangitis (PBC), but some people do not respond well to UDCA. It reported that the combination of fenofibrate and UDCA can improve the clinical indices in these patients. However, more high-quality evide...

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Bibliographic Details
Main Authors: Xuan Guoyun, Ding Dawei, Liu Ning, Hu Yinan, Yang Fangfang, Tian Siyuan, Sun Hao, Yang Jiaqi, Xu Ang, Guo Guanya, Chen Xi, Shang Yulong, Han Ying
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
primary biliary cholangitis
monotherapy
meta-analysis
clinical trial
fenofibrate
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.948362/full

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