Establishment of a gnotobiotic pig model of Clostridioides difficile infection and disease

Establishment of a gnotobiotic pig model of Clostridioides difficile infection and disease

Abstract Clostridioides difficile (C. difficile) is a gram-positive, spore-forming, anaerobic bacterium known to be the most common cause of hospital-acquired and antibiotic-associated diarrhea. C. difficile infection rates are on the rise worldwide and treatment options are limited, indicating a cl...

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Bibliographic Details
Main Authors: Charlotte Nyblade, Viviana Parreno, Peng Zhou, Casey Hensley, Vanessa Oakes, Hassan M. Mahsoub, Kelsey Kiley, Maggie Frazier, Annie Frazier, Yongrong Zhang, Hanping Feng, Lijuan Yuan
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Gut Pathogens
Subjects:
Clostridioides difficile infection/illness (CDI)
Gnotobiotic pigs
Pseudomembranous colitis (PMC)
Online Access:https://doi.org/10.1186/s13099-022-00496-y

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