Retinoblastoma Outcomes in a Tertiary Hospital in Northern Luzon, The Philippines: A 15-Year Experience
Abstract Roland Joseph D. Tan Objective To describe the demographics, clinical profile, and outcomes of retinoblastoma patients seen in a tertiary hospital in northern Luzon. Ma...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2022-04-01
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| Series: | South Asian Journal of Cancer |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1739179 |
| _version_ | 1797987244725764096 |
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| author | Roland Joseph D. Tan Kathleen Faye B. Ballesteros |
| author_facet | Roland Joseph D. Tan Kathleen Faye B. Ballesteros |
| author_sort | Roland Joseph D. Tan |
| collection | DOAJ |
| description | Abstract
Roland Joseph D. Tan
Objective To describe the demographics, clinical profile, and outcomes of retinoblastoma patients seen in a tertiary hospital in northern Luzon.
Materials and Methods This is a retrospective cross-sectional study of retinoblastoma patients at the departments of ophthalmology and pediatrics of a tertiary hospital in northern Luzon from 2005 to 2020.
Results A total of 47 patients involving 53 eyes were included. Twenty nine (62%) are male and forty one (87%) had unilateral retinoblastoma. Mean age at consult was 24 ± 17 months, and mean interval from onset of symptoms to consult was 10 ± 11 months. Two (4%) had family history of retinoblastoma. Twenty-two (47%) patients had intraocular involvement. Leukocoria was the most common presenting symptoms at 62%. Overall survival was 53% with mean follow-up period of 24 ± 24 months. Difference in survival rates based on the extent of involvement was statistically significant (p < 0.001).
Conclusion This is the first study that provided data on demographics, clinical profile, and outcomes of retinoblastoma patients in northern Luzon and the only study with data on clinical outcomes of retinoblastoma patients in The Philippines. Extraocular involvement is a significant factor in the low survival of retinoblastoma patients despite improvement in its management. |
| first_indexed | 2024-04-11T07:44:45Z |
| format | Article |
| id | doaj.art-16bb64202d354df58bcbfcd41f7d096d |
| institution | Directory Open Access Journal |
| issn | 2278-330X 2278-4306 |
| language | English |
| last_indexed | 2024-04-11T07:44:45Z |
| publishDate | 2022-04-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | South Asian Journal of Cancer |
| spelling | doaj.art-16bb64202d354df58bcbfcd41f7d096d2022-12-22T04:36:19ZengThieme Medical and Scientific Publishers Pvt. Ltd.South Asian Journal of Cancer2278-330X2278-43062022-04-01110216016310.1055/s-0041-1739179Retinoblastoma Outcomes in a Tertiary Hospital in Northern Luzon, The Philippines: A 15-Year ExperienceRoland Joseph D. Tan0Kathleen Faye B. Ballesteros1Department of Ophthalmology, Baguio General Hospital and Medical Center, Baguio City, PhilippinesDepartment of Ophthalmology, Baguio General Hospital and Medical Center, Baguio City, PhilippinesAbstract Roland Joseph D. Tan Objective To describe the demographics, clinical profile, and outcomes of retinoblastoma patients seen in a tertiary hospital in northern Luzon. Materials and Methods This is a retrospective cross-sectional study of retinoblastoma patients at the departments of ophthalmology and pediatrics of a tertiary hospital in northern Luzon from 2005 to 2020. Results A total of 47 patients involving 53 eyes were included. Twenty nine (62%) are male and forty one (87%) had unilateral retinoblastoma. Mean age at consult was 24 ± 17 months, and mean interval from onset of symptoms to consult was 10 ± 11 months. Two (4%) had family history of retinoblastoma. Twenty-two (47%) patients had intraocular involvement. Leukocoria was the most common presenting symptoms at 62%. Overall survival was 53% with mean follow-up period of 24 ± 24 months. Difference in survival rates based on the extent of involvement was statistically significant (p < 0.001). Conclusion This is the first study that provided data on demographics, clinical profile, and outcomes of retinoblastoma patients in northern Luzon and the only study with data on clinical outcomes of retinoblastoma patients in The Philippines. Extraocular involvement is a significant factor in the low survival of retinoblastoma patients despite improvement in its management.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1739179retinoblastomasurvivaloutcomesnorthern luzonphilippines |
| spellingShingle | Roland Joseph D. Tan Kathleen Faye B. Ballesteros Retinoblastoma Outcomes in a Tertiary Hospital in Northern Luzon, The Philippines: A 15-Year Experience South Asian Journal of Cancer retinoblastoma survival outcomes northern luzon philippines |
| title | Retinoblastoma Outcomes in a Tertiary Hospital in Northern Luzon, The Philippines: A 15-Year Experience |
| title_full | Retinoblastoma Outcomes in a Tertiary Hospital in Northern Luzon, The Philippines: A 15-Year Experience |
| title_fullStr | Retinoblastoma Outcomes in a Tertiary Hospital in Northern Luzon, The Philippines: A 15-Year Experience |
| title_full_unstemmed | Retinoblastoma Outcomes in a Tertiary Hospital in Northern Luzon, The Philippines: A 15-Year Experience |
| title_short | Retinoblastoma Outcomes in a Tertiary Hospital in Northern Luzon, The Philippines: A 15-Year Experience |
| title_sort | retinoblastoma outcomes in a tertiary hospital in northern luzon the philippines a 15 year experience |
| topic | retinoblastoma survival outcomes northern luzon philippines |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1739179 |
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