Insidious fatal perforation of palate: A diagnostic challenge
Granulomatosis with polyangiitis (GPA) is considered as a systemic triad of necrotizing granulomatous vasculitis of the upper and lower respiratory tracts (pulmonary vasculitis) and a rapidly progressive glomerulonephritis. Few cases of a superficial form with only oral involvement are reported. The...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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Series: | Journal of Indian Academy of Oral Medicine and Radiology |
Subjects: | |
Online Access: | http://www.jiaomr.in/article.asp?issn=0972-1363;year=2020;volume=32;issue=3;spage=293;epage=296;aulast=Prasad |
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author | R Guru Prasad Akshay Sujith Neeta Sharma Brijesh Kumar |
author_facet | R Guru Prasad Akshay Sujith Neeta Sharma Brijesh Kumar |
author_sort | R Guru Prasad |
collection | DOAJ |
description | Granulomatosis with polyangiitis (GPA) is considered as a systemic triad of necrotizing granulomatous vasculitis of the upper and lower respiratory tracts (pulmonary vasculitis) and a rapidly progressive glomerulonephritis. Few cases of a superficial form with only oral involvement are reported. The purpose of this article is to describe the steps in reaching a conclusive diagnosis in lesions involving the palate. Since in most cases the histopathological report will turn inconclusive, proper clinical evaluation and definitive diagnostic test like the estimation of cytoplasmic-antineutrophilic cytoplasmic antibody will be mandatory for obtaining a conclusive result. |
first_indexed | 2024-12-10T21:33:56Z |
format | Article |
id | doaj.art-16bf017ff7a94b758bae00b31684674e |
institution | Directory Open Access Journal |
issn | 0972-1363 |
language | English |
last_indexed | 2024-12-10T21:33:56Z |
publishDate | 2020-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Journal of Indian Academy of Oral Medicine and Radiology |
spelling | doaj.art-16bf017ff7a94b758bae00b31684674e2022-12-22T01:32:42ZengWolters Kluwer Medknow PublicationsJournal of Indian Academy of Oral Medicine and Radiology0972-13632020-01-0132329329610.4103/jiaomr.jiaomr_52_20Insidious fatal perforation of palate: A diagnostic challengeR Guru PrasadAkshay SujithNeeta SharmaBrijesh KumarGranulomatosis with polyangiitis (GPA) is considered as a systemic triad of necrotizing granulomatous vasculitis of the upper and lower respiratory tracts (pulmonary vasculitis) and a rapidly progressive glomerulonephritis. Few cases of a superficial form with only oral involvement are reported. The purpose of this article is to describe the steps in reaching a conclusive diagnosis in lesions involving the palate. Since in most cases the histopathological report will turn inconclusive, proper clinical evaluation and definitive diagnostic test like the estimation of cytoplasmic-antineutrophilic cytoplasmic antibody will be mandatory for obtaining a conclusive result.http://www.jiaomr.in/article.asp?issn=0972-1363;year=2020;volume=32;issue=3;spage=293;epage=296;aulast=Prasadantineutrophilic cytoplasmic antibodiesgranulomatosis polyangiitisperforation of palatewegener's granulomatosis |
spellingShingle | R Guru Prasad Akshay Sujith Neeta Sharma Brijesh Kumar Insidious fatal perforation of palate: A diagnostic challenge Journal of Indian Academy of Oral Medicine and Radiology antineutrophilic cytoplasmic antibodies granulomatosis polyangiitis perforation of palate wegener's granulomatosis |
title | Insidious fatal perforation of palate: A diagnostic challenge |
title_full | Insidious fatal perforation of palate: A diagnostic challenge |
title_fullStr | Insidious fatal perforation of palate: A diagnostic challenge |
title_full_unstemmed | Insidious fatal perforation of palate: A diagnostic challenge |
title_short | Insidious fatal perforation of palate: A diagnostic challenge |
title_sort | insidious fatal perforation of palate a diagnostic challenge |
topic | antineutrophilic cytoplasmic antibodies granulomatosis polyangiitis perforation of palate wegener's granulomatosis |
url | http://www.jiaomr.in/article.asp?issn=0972-1363;year=2020;volume=32;issue=3;spage=293;epage=296;aulast=Prasad |
work_keys_str_mv | AT rguruprasad insidiousfatalperforationofpalateadiagnosticchallenge AT akshaysujith insidiousfatalperforationofpalateadiagnosticchallenge AT neetasharma insidiousfatalperforationofpalateadiagnosticchallenge AT brijeshkumar insidiousfatalperforationofpalateadiagnosticchallenge |