<i>mcr-1</i>-Mediated In Vitro Inhibition of Plasmid Transfer Is Reversed by the Intestinal Environment

<i>mcr-1</i>-Mediated In Vitro Inhibition of Plasmid Transfer Is Reversed by the Intestinal Environment

Colistin is regarded as an antibiotic of last resort against multidrug-resistant Gram-negative bacteria, including <i>Klebsiella pneumoniae</i> and <i>Escherichia coli</i>. Colistin resistance is acquired by microorganisms via chromosome-mediated mutations or plasmid-mediated...

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Bibliographic Details
Main Authors: Xiaoman Yang, Rundong Shu, Leqi Hou, Panpan Ren, Xin Lu, Zhi Huang, Zengtao Zhong, Hui Wang
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Antibiotics
Subjects:
<i>mcr-1</i>
colistin resistance
conjugation
bile salt
<i>Klebsiella pneumoniae</i>
<i>Escherichia coli</i>
Online Access:https://www.mdpi.com/2079-6382/11/7/875

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