A statistical framework for differential pseudotime analysis with multiple single-cell RNA-seq samples

Abstract Pseudotime analysis with single-cell RNA-sequencing (scRNA-seq) data has been widely used to study dynamic gene regulatory programs along continuous biological processes. While many methods have been developed to infer the pseudotemporal trajectories of cells within a biological sample, it...

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Bibliographic Details
Main Authors: Wenpin Hou, Zhicheng Ji, Zeyu Chen, E. John Wherry, Stephanie C. Hicks, Hongkai Ji
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42841-y

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