A comparative study of 1D and 3D hemodynamics in patient-specific hepatic portal vein networks
The development of software for use in clinical practice is often associated with many requirements and restrictions set not only by the medical doctors, but also by the hospital’s budget. To meet the requirement of reliable software, which is able to provide results within a short time period and w...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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University of West Bohemia
2014-12-01
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| Series: | Applied and Computational Mechanics |
| Subjects: | |
| Online Access: | http://www.kme.zcu.cz/acm/acm/article/view/279/301 |
| _version_ | 1818353810014208000 |
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| author | Jonášová A. Bublík O. Vimmr J. |
| author_facet | Jonášová A. Bublík O. Vimmr J. |
| author_sort | Jonášová A. |
| collection | DOAJ |
| description | The development of software for use in clinical practice is often associated with many requirements and restrictions set not only by the medical doctors, but also by the hospital’s budget. To meet the requirement of reliable software, which is able to provide results within a short time period and with minimal computational demand, a certain measure of modelling simplification is usually inevitable. In case of blood flow simulations carried out in large vascular networks such as the one created by the hepatic portal vein, simplifications are made by necessity.
The most often employed simplification includes the approach in the form of dimensional reduction, when the 3D model of a large vascular network is substituted with its 1D counterpart. In this context, a question naturally arises, how this reduction can affect the simulation accuracy and its outcome. In this paper, we try to answer this question by performing a quantitative comparison of 3D and 1D flow models in two patient-specific hepatic portal vein networks. The numerical simulations are carried out under average flow conditions and with the application of the three-element Windkessel model, which is able to approximate the downstream flow resistance of real hepatic tissue. The obtained results show that, although the 1D model can never truly substitute the 3D model, its easy implementation, time-saving model preparation and almost no demands on computer technology dominate as advantages over obvious but moderate modelling errors arising from the performed dimensional reduction. |
| first_indexed | 2024-12-13T19:15:26Z |
| format | Article |
| id | doaj.art-16d31bf4604e468a94e477bdb41e6c75 |
| institution | Directory Open Access Journal |
| issn | 1802-680X 2336-1182 |
| language | English |
| last_indexed | 2024-12-13T19:15:26Z |
| publishDate | 2014-12-01 |
| publisher | University of West Bohemia |
| record_format | Article |
| series | Applied and Computational Mechanics |
| spelling | doaj.art-16d31bf4604e468a94e477bdb41e6c752022-12-21T23:34:17ZengUniversity of West BohemiaApplied and Computational Mechanics1802-680X2336-11822014-12-0182177186A comparative study of 1D and 3D hemodynamics in patient-specific hepatic portal vein networksJonášová A.0Bublík O.1Vimmr J.2University of West Bohemia, NTIS – New Technologies for the Information Society, Plzen, Czech RepublicUniversity of West Bohemia, NTIS – New Technologies for the Information Society, Plzen, Czech RepublicUniversity of West Bohemia, NTIS – New Technologies for the Information Society, Plzen, Czech RepublicThe development of software for use in clinical practice is often associated with many requirements and restrictions set not only by the medical doctors, but also by the hospital’s budget. To meet the requirement of reliable software, which is able to provide results within a short time period and with minimal computational demand, a certain measure of modelling simplification is usually inevitable. In case of blood flow simulations carried out in large vascular networks such as the one created by the hepatic portal vein, simplifications are made by necessity. The most often employed simplification includes the approach in the form of dimensional reduction, when the 3D model of a large vascular network is substituted with its 1D counterpart. In this context, a question naturally arises, how this reduction can affect the simulation accuracy and its outcome. In this paper, we try to answer this question by performing a quantitative comparison of 3D and 1D flow models in two patient-specific hepatic portal vein networks. The numerical simulations are carried out under average flow conditions and with the application of the three-element Windkessel model, which is able to approximate the downstream flow resistance of real hepatic tissue. The obtained results show that, although the 1D model can never truly substitute the 3D model, its easy implementation, time-saving model preparation and almost no demands on computer technology dominate as advantages over obvious but moderate modelling errors arising from the performed dimensional reduction.http://www.kme.zcu.cz/acm/acm/article/view/279/301patient-specific modelblood flowfinite volume methodWindkessel model |
| spellingShingle | Jonášová A. Bublík O. Vimmr J. A comparative study of 1D and 3D hemodynamics in patient-specific hepatic portal vein networks Applied and Computational Mechanics patient-specific model blood flow finite volume method Windkessel model |
| title | A comparative study of 1D and 3D hemodynamics in patient-specific hepatic portal vein networks |
| title_full | A comparative study of 1D and 3D hemodynamics in patient-specific hepatic portal vein networks |
| title_fullStr | A comparative study of 1D and 3D hemodynamics in patient-specific hepatic portal vein networks |
| title_full_unstemmed | A comparative study of 1D and 3D hemodynamics in patient-specific hepatic portal vein networks |
| title_short | A comparative study of 1D and 3D hemodynamics in patient-specific hepatic portal vein networks |
| title_sort | comparative study of 1d and 3d hemodynamics in patient specific hepatic portal vein networks |
| topic | patient-specific model blood flow finite volume method Windkessel model |
| url | http://www.kme.zcu.cz/acm/acm/article/view/279/301 |
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