<it>ABCB1 </it>genotypes and haplotypes in patients with dementia and age-matched non-demented control patients

<p>Abstract</p> <p>Amyloid β is an <it>in vitro </it>substrate for P-glycoprotein (P-gp), an efflux pump at the blood brain barrier (BBB). The Multi Drug Resistance (<it>ABCB1</it>) gene, encoding for P-gp, is highly polymorphic and this may result in a chan...

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Bibliographic Details
Main Authors: Frankfort Suzanne V, Doodeman Valerie D, Bakker Remco, Tulner Linda R, van Campen Jos PCM, Smits Paul HM, Beijnen Jos H
Format: Article
Language:English
Published: BMC 2006-09-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/1/1/13