Improving radio-chemotherapy efficacy of prostate cancer by co-deliverying docetaxel and dbait with biodegradable nanoparticles

Improving radio-chemotherapy efficacy of prostate cancer by co-deliverying docetaxel and dbait with biodegradable nanoparticles

AbstractCombining DNA damage repair inhibitors and chemotherapeutic agents is an emerging strategy in cancer treatment. In this study, we engineered the polycation nanoparticle (NP), which co-encapsulated DNA damage repair inhibitor Dbait and chemotherapeutic drug Docetaxel (Dtxl), using H1 nanopoly...

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Bibliographic Details
Main Authors: Nianli Liu, Jiayin Ji, Hui Qiu, Zhiying Shao, Xin Wen, Aoxing Chen, Senbang Yao, Xingying Zhang, Hong Yao, Longzhen Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Subjects:
Nanoparticle
DNA damage repair inhibitor
Dbait
radiosensitizer
castration-resistant prostate cancer
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2019.1703726

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