The Chick Embryo Xenograft Model for Malignant Pleural Mesothelioma: A Cost and Time Efficient 3Rs Model for Drug Target Evaluation

The Chick Embryo Xenograft Model for Malignant Pleural Mesothelioma: A Cost and Time Efficient 3Rs Model for Drug Target Evaluation

Malignant pleural mesothelioma (MPM) has limited treatment options and poor prognosis. Frequent inactivation of the tumour suppressors <i>BAP1</i>, <i>NF2</i> and <i>P16</i> may differentially sensitise tumours to treatments. We have established chick chorioallant...

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Bibliographic Details
Main Authors: Sarah E. Barnett, Anne Herrmann, Liam Shaw, Elisabeth N. Gash, Harish Poptani, Joseph J. Sacco, Judy M. Coulson
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
mesothelioma
chick embryo
CAM
xenograft
bioluminescence
fluorescence
Online Access:https://www.mdpi.com/2072-6694/14/23/5836

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https://www.mdpi.com/2072-6694/14/23/5836

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