Data mining: traditional spring festival associated with hypercholesterolemia
Abstract Background Serum lipid concentrations are affected by long-term high-fat diets; thus, we hypothesize that lipid levels increase after the Spring Festival in China. Method In total, 20,192 individuals (male: n=10,108, female: n=10,084) were enrolled in this retrospective cross-sectional stud...
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| Format: | Article |
| Language: | English |
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BMC
2021-11-01
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| Series: | BMC Cardiovascular Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12872-021-02328-4 |
| _version_ | 1818433564033679360 |
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| author | Danchen Wang Yutong Zou Honglei Li Songlin Yu Liangyu Xia Xinqi Cheng Ling Qiu Tengda Xu |
| author_facet | Danchen Wang Yutong Zou Honglei Li Songlin Yu Liangyu Xia Xinqi Cheng Ling Qiu Tengda Xu |
| author_sort | Danchen Wang |
| collection | DOAJ |
| description | Abstract Background Serum lipid concentrations are affected by long-term high-fat diets; thus, we hypothesize that lipid levels increase after the Spring Festival in China. Method In total, 20,192 individuals (male: n=10,108, female: n=10,084) were enrolled in this retrospective cross-sectional study based on clinical data from the Laboratory Information System (LIS) and Hospital Information System (HIS) in Peking Union Medical College Hospital from 2014 to 2018. Total cholesterol (TC), triglycerides (TGs), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were analyzed. Results The serum TC [male vs. female: (4.71 ± 0.90 vs. 4.56 ± 0.85) mmol/L], TG [male vs. female: (1.71 ± 1.56 vs. 1.02 ± 0.68) mmol/L], and LDL-C [male vs. female: (3.01 ± 0.77 vs. 2.73 ± 0.74) mmol/L] levels were significantly higher in males than in females (P < 0.001); serum HDL-C [male vs. female: (1.18 ± 0.28 vs. 1.50 ± 0.34) mmol/L] was significantly lower in males (P < 0.001). In February, the TC, TG, and LDL-C levels were 8.4%, 16.3%, and 9.3% higher than the lowest levels recorded, respectively. The prevalence of dyslipidemia of the two weeks before the Spring festival was significantly lower than that of the first week after the Spring festival (43.6% (168/385) vs. 54.1% (126/233), P=0.007). Additionally, the prevalence of dyslipidemia was statistically higher in the first week after the Spring Festival than in May–January. Conclusion Higher TC, TG, and LDL-C in winter could be associated with high-fat diets during the Spring Festival. The Spring Festival was immediately followed by a higher lipid concentrations. Thus, we don't recommend lipid assessment or physical examination immediately after the holiday especially Spring festival. |
| first_indexed | 2024-12-14T16:23:06Z |
| format | Article |
| id | doaj.art-16d7af5f54644a8cb2b673d45596ea78 |
| institution | Directory Open Access Journal |
| issn | 1471-2261 |
| language | English |
| last_indexed | 2024-12-14T16:23:06Z |
| publishDate | 2021-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj.art-16d7af5f54644a8cb2b673d45596ea782022-12-21T22:54:46ZengBMCBMC Cardiovascular Disorders1471-22612021-11-012111710.1186/s12872-021-02328-4Data mining: traditional spring festival associated with hypercholesterolemiaDanchen Wang0Yutong Zou1Honglei Li2Songlin Yu3Liangyu Xia4Xinqi Cheng5Ling Qiu6Tengda Xu7Department of Laboratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesDepartment of Laboratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesDepartment of Laboratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesDepartment of Laboratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesDepartment of Laboratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesDepartment of Laboratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesDepartment of Laboratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesDepartment of Health Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesAbstract Background Serum lipid concentrations are affected by long-term high-fat diets; thus, we hypothesize that lipid levels increase after the Spring Festival in China. Method In total, 20,192 individuals (male: n=10,108, female: n=10,084) were enrolled in this retrospective cross-sectional study based on clinical data from the Laboratory Information System (LIS) and Hospital Information System (HIS) in Peking Union Medical College Hospital from 2014 to 2018. Total cholesterol (TC), triglycerides (TGs), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were analyzed. Results The serum TC [male vs. female: (4.71 ± 0.90 vs. 4.56 ± 0.85) mmol/L], TG [male vs. female: (1.71 ± 1.56 vs. 1.02 ± 0.68) mmol/L], and LDL-C [male vs. female: (3.01 ± 0.77 vs. 2.73 ± 0.74) mmol/L] levels were significantly higher in males than in females (P < 0.001); serum HDL-C [male vs. female: (1.18 ± 0.28 vs. 1.50 ± 0.34) mmol/L] was significantly lower in males (P < 0.001). In February, the TC, TG, and LDL-C levels were 8.4%, 16.3%, and 9.3% higher than the lowest levels recorded, respectively. The prevalence of dyslipidemia of the two weeks before the Spring festival was significantly lower than that of the first week after the Spring festival (43.6% (168/385) vs. 54.1% (126/233), P=0.007). Additionally, the prevalence of dyslipidemia was statistically higher in the first week after the Spring Festival than in May–January. Conclusion Higher TC, TG, and LDL-C in winter could be associated with high-fat diets during the Spring Festival. The Spring Festival was immediately followed by a higher lipid concentrations. Thus, we don't recommend lipid assessment or physical examination immediately after the holiday especially Spring festival.https://doi.org/10.1186/s12872-021-02328-4Lipid profileHypercholesterolemiaChineseDyslipidemiaSpring festival |
| spellingShingle | Danchen Wang Yutong Zou Honglei Li Songlin Yu Liangyu Xia Xinqi Cheng Ling Qiu Tengda Xu Data mining: traditional spring festival associated with hypercholesterolemia BMC Cardiovascular Disorders Lipid profile Hypercholesterolemia Chinese Dyslipidemia Spring festival |
| title | Data mining: traditional spring festival associated with hypercholesterolemia |
| title_full | Data mining: traditional spring festival associated with hypercholesterolemia |
| title_fullStr | Data mining: traditional spring festival associated with hypercholesterolemia |
| title_full_unstemmed | Data mining: traditional spring festival associated with hypercholesterolemia |
| title_short | Data mining: traditional spring festival associated with hypercholesterolemia |
| title_sort | data mining traditional spring festival associated with hypercholesterolemia |
| topic | Lipid profile Hypercholesterolemia Chinese Dyslipidemia Spring festival |
| url | https://doi.org/10.1186/s12872-021-02328-4 |
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