Angiotensin II Induces C-Reactive Protein Expression via AT1-ROS-MAPK-NF-κB Signal Pathway in Hepatocytes

Angiotensin II Induces C-Reactive Protein Expression via AT1-ROS-MAPK-NF-κB Signal Pathway in Hepatocytes

Background: C-reactive protein (CRP) participates in development of inflammatory diseases. Hepatocytes are a major contributor of circulating CRP. Although angiotensin II (Ang II) is known to evoke inflammatory response, it remains unknown whether Ang II induces CRP expression in hepatocytes. The pr...

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Bibliographic Details
Main Authors: Jingjing Zhao, Juntian Liu, Xiaoming Pang, Shuyue Wang, Di Wu, Xiaolu Zhang, Liuxin Feng
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
C-reactive protein
Angiotensin II
Hepatocytes
Liver
Inflammation
Atherosclerosis
Online Access:http://www.karger.com/Article/FullText/354461

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