De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency
Summary: CpG islands (CGIs) including those at imprinting control regions (ICRs) are protected from de novo methylation in somatic cells. However, many cancers often exhibit CGI hypermethylation, implying that the machinery is impaired in cancer cells. Here, we conducted a comprehensive analysis of...
| প্রধান লেখক: | , , , , , , , , , , , , |
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| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
| প্রকাশিত: |
Elsevier
2019-05-01
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| মালা: | Stem Cell Reports |
| অনলাইন ব্যবহার করুন: | http://www.sciencedirect.com/science/article/pii/S2213671119301304 |