Comparison of the methylglyoxal scavenging effects of kaempferol and glutathione and the consequences for the toxicity of methylglyoxal in SH-SY5Y cells

Comparison of the methylglyoxal scavenging effects of kaempferol and glutathione and the consequences for the toxicity of methylglyoxal in SH-SY5Y cells

This study aimed to characterize the methylglyoxal (MGO) scavenging capacity of glutathione (GSH) and kaempferol in more detail with special emphasis on the possible reversible nature of the adduct formation and their competition for MGO, and the safety consequences of their MGO-scavenging effects....

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Bibliographic Details
Main Authors: Liang Zheng, Wouter Bakker, Ignacio Miro Estruch, Frances Widjaja, Ivonne M.C.M. Rietjens
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Food Chemistry: X
Subjects:
Methylglyoxal
Kaempferol
Glutathione
Adduct formation
Cytotoxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2590157523003632

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