Influence of ligand structure on anticancer and antioxidant properties of rhenium cluster compounds
Under the model growth of T8 Guerin’s carcinoma in rats we studied the anticancer activity of the system rhenium-platinum, which includes cis-dicarboxylates of rhenium (III) with different alkyl ligands, erythrocytes number and its morphological structure, erythrocytic stability, blood haemoglobin c...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Oles Honchar Dnipropetrovsk National University
2009-11-01
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| Series: | Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ |
| Online Access: | http://ecology.dp.ua/index.php/ECO/article/view/212 |
| Summary: | Under the model growth of T8 Guerin’s carcinoma in rats we studied the anticancer activity of the system rhenium-platinum, which includes cis-dicarboxylates of rhenium (III) with different alkyl ligands, erythrocytes number and its morphological structure, erythrocytic stability, blood haemoglobin concentration, catalase activity and concentration of TBA-active products in the rats blood plasma. The renium-platinum system had considerable antioxidat effect and prevented the growth of tumour, that was maximal for a compound with the pivalate ligand. |
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| ISSN: | 2310-0842 2312-301X |