Unusual Presentation of Granulomatosis With Polyangitis (Wegener's Granulomatosis)
Objective: To present a case of unusual presentations of granulomatosis with polyangitis (Wegener’s granulomatosis) with parotid swelling and intractable otitis externa. Material and method: A 22-year-old male patient presented with left sided otitis externa with left sided parotid swelling and b...
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| Format: | Article |
| Language: | English |
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The Association of Otolaryngologists of India, West Bengal
2016-04-01
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| Series: | Bengal Journal of Otolaryngology and Head Neck Surgery |
| Subjects: | |
| Online Access: | https://bjohns.in/journal3/index.php/bjohns/article/view/74 |
| _version_ | 1827334241482964992 |
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| author | Anirban Ghosh Somnath Saha Sarbani Chattopadhyay |
| author_facet | Anirban Ghosh Somnath Saha Sarbani Chattopadhyay |
| author_sort | Anirban Ghosh |
| collection | DOAJ |
| description | Objective: To present a case of unusual presentations of granulomatosis with polyangitis (Wegener’s granulomatosis) with parotid swelling and intractable otitis externa.
Material and method: A 22-year-old male patient presented with left sided otitis externa with left sided parotid swelling and bilateral nasal obstruction for last two weeks. CT scan of paranasal sinuses showed homogenous mass in both maxillary antra and nasal cavities. FNAC from the parotid swelling was suggestive of granulomatous disease and endoscopic biopsy from the nasal mass showed features of granulomatosis with polyangitis (Wegener’s granulomatosis). CT scan of chest revealed multiple cysts within the lung parenchyma; urine examination showed RBC and pus cells. Renal biopsy showed focal segmental glomerulonephritis. c-ANCA was highly positive and thus the diagnosis of Wegener’s granulomatosis was made.
Result: Patient received cyclophosphamide and prednisolone immunsuppressive therapy for one year, which showed marked clinical improvement.
Conclusion: Granulomatosis with polyangitis (Wegener’s granulomatosis) is not an uncommon entity for otolarygologists. Its usual presentation mimics chronic rhinosinusitis; but presentations like otitis externa and parotid swelling are rare for this disease. |
| first_indexed | 2024-03-07T17:51:31Z |
| format | Article |
| id | doaj.art-16e88053f6504619b5149610260b8912 |
| institution | Directory Open Access Journal |
| issn | 2395-2407 |
| language | English |
| last_indexed | 2024-03-07T17:51:31Z |
| publishDate | 2016-04-01 |
| publisher | The Association of Otolaryngologists of India, West Bengal |
| record_format | Article |
| series | Bengal Journal of Otolaryngology and Head Neck Surgery |
| spelling | doaj.art-16e88053f6504619b5149610260b89122024-03-02T13:52:54ZengThe Association of Otolaryngologists of India, West BengalBengal Journal of Otolaryngology and Head Neck Surgery2395-24072016-04-0124110.47210/bjohns.2016.v24i1.74Unusual Presentation of Granulomatosis With Polyangitis (Wegener's Granulomatosis)Anirban Ghosh0Somnath Saha1Sarbani Chattopadhyay2Hope Nursing HomeDept of ENT, NRS Medical College, KolkataDept of Pathology, Medical College, KolkataObjective: To present a case of unusual presentations of granulomatosis with polyangitis (Wegener’s granulomatosis) with parotid swelling and intractable otitis externa. Material and method: A 22-year-old male patient presented with left sided otitis externa with left sided parotid swelling and bilateral nasal obstruction for last two weeks. CT scan of paranasal sinuses showed homogenous mass in both maxillary antra and nasal cavities. FNAC from the parotid swelling was suggestive of granulomatous disease and endoscopic biopsy from the nasal mass showed features of granulomatosis with polyangitis (Wegener’s granulomatosis). CT scan of chest revealed multiple cysts within the lung parenchyma; urine examination showed RBC and pus cells. Renal biopsy showed focal segmental glomerulonephritis. c-ANCA was highly positive and thus the diagnosis of Wegener’s granulomatosis was made. Result: Patient received cyclophosphamide and prednisolone immunsuppressive therapy for one year, which showed marked clinical improvement. Conclusion: Granulomatosis with polyangitis (Wegener’s granulomatosis) is not an uncommon entity for otolarygologists. Its usual presentation mimics chronic rhinosinusitis; but presentations like otitis externa and parotid swelling are rare for this disease.https://bjohns.in/journal3/index.php/bjohns/article/view/74Granulomatosis with PolyangiitisOtitis ExternaNasal ObstructionParotid GlandEndoscopyBiopsy |
| spellingShingle | Anirban Ghosh Somnath Saha Sarbani Chattopadhyay Unusual Presentation of Granulomatosis With Polyangitis (Wegener's Granulomatosis) Bengal Journal of Otolaryngology and Head Neck Surgery Granulomatosis with Polyangiitis Otitis Externa Nasal Obstruction Parotid Gland Endoscopy Biopsy |
| title | Unusual Presentation of Granulomatosis With Polyangitis (Wegener's Granulomatosis) |
| title_full | Unusual Presentation of Granulomatosis With Polyangitis (Wegener's Granulomatosis) |
| title_fullStr | Unusual Presentation of Granulomatosis With Polyangitis (Wegener's Granulomatosis) |
| title_full_unstemmed | Unusual Presentation of Granulomatosis With Polyangitis (Wegener's Granulomatosis) |
| title_short | Unusual Presentation of Granulomatosis With Polyangitis (Wegener's Granulomatosis) |
| title_sort | unusual presentation of granulomatosis with polyangitis wegener s granulomatosis |
| topic | Granulomatosis with Polyangiitis Otitis Externa Nasal Obstruction Parotid Gland Endoscopy Biopsy |
| url | https://bjohns.in/journal3/index.php/bjohns/article/view/74 |
| work_keys_str_mv | AT anirbanghosh unusualpresentationofgranulomatosiswithpolyangitiswegenersgranulomatosis AT somnathsaha unusualpresentationofgranulomatosiswithpolyangitiswegenersgranulomatosis AT sarbanichattopadhyay unusualpresentationofgranulomatosiswithpolyangitiswegenersgranulomatosis |