Unexpected Tumor Rupture in a Case of Treatment-naïve Neuroblastoma - A Mortality Experience from a Tertiary Medical Institution
Neuroblastoma (NBL) is one of the most common extracranial neoplasms in children. Mortality is often attributed to treatment-related adverse events, sepsis secondary to immunocompromised status, and multi-organ failure resulting from advanced illness. Cases of NBL initially presenting with life-thre...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2024-03-01
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| Series: | The Journal of Pediatric Academy |
| Subjects: | |
| Online Access: | https://jpediatricacademy.com/index.php/jpa/article/view/254 |
| _version_ | 1797228820777926656 |
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| author | Wan-Ju Lee Yi-Lun Wang Tsung-Yen Chang |
| author_facet | Wan-Ju Lee Yi-Lun Wang Tsung-Yen Chang |
| author_sort | Wan-Ju Lee |
| collection | DOAJ |
| description | Neuroblastoma (NBL) is one of the most common extracranial neoplasms in children. Mortality is often attributed to treatment-related adverse events, sepsis secondary to immunocompromised status, and multi-organ failure resulting from advanced illness. Cases of NBL initially presenting with life-threatening events are rare. Here, we present a fatal NBL case that initially manifested profound anemia and coagulopathy, which later progressed to hemorrhagic shock due to tumor rupture. |
| first_indexed | 2024-04-24T15:02:47Z |
| format | Article |
| id | doaj.art-16ea75a722934119a12a633e3badfe45 |
| institution | Directory Open Access Journal |
| issn | 2718-0875 |
| language | English |
| last_indexed | 2024-04-24T15:02:47Z |
| publishDate | 2024-03-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | The Journal of Pediatric Academy |
| spelling | doaj.art-16ea75a722934119a12a633e3badfe452024-04-02T14:18:20ZengGalenos Publishing HouseThe Journal of Pediatric Academy2718-08752024-03-0151343610.4274/jpea.2024.254209Unexpected Tumor Rupture in a Case of Treatment-naïve Neuroblastoma - A Mortality Experience from a Tertiary Medical InstitutionWan-Ju Lee0Yi-Lun Wang1https://orcid.org/0000-0002-0003-5153Tsung-Yen Chang2https://orcid.org/0000-0003-1123-4235Mackay Memorial Hospital, Clinic of Radiation Oncology, Taipei, TaiwanChang Gung Children’s Hospital, Clinic of Pediatrics, Divisions of Hematology and Oncology, Taoyuan, TaiwanChang Gung Children’s Hospital, Clinic of Pediatrics, Divisions of Hematology and Oncology, Taoyuan, TaiwanNeuroblastoma (NBL) is one of the most common extracranial neoplasms in children. Mortality is often attributed to treatment-related adverse events, sepsis secondary to immunocompromised status, and multi-organ failure resulting from advanced illness. Cases of NBL initially presenting with life-threatening events are rare. Here, we present a fatal NBL case that initially manifested profound anemia and coagulopathy, which later progressed to hemorrhagic shock due to tumor rupture.https://jpediatricacademy.com/index.php/jpa/article/view/254mortalityneuroblastomaoncologypediatrics |
| spellingShingle | Wan-Ju Lee Yi-Lun Wang Tsung-Yen Chang Unexpected Tumor Rupture in a Case of Treatment-naïve Neuroblastoma - A Mortality Experience from a Tertiary Medical Institution The Journal of Pediatric Academy mortality neuroblastoma oncology pediatrics |
| title | Unexpected Tumor Rupture in a Case of Treatment-naïve Neuroblastoma - A Mortality Experience from a Tertiary Medical Institution |
| title_full | Unexpected Tumor Rupture in a Case of Treatment-naïve Neuroblastoma - A Mortality Experience from a Tertiary Medical Institution |
| title_fullStr | Unexpected Tumor Rupture in a Case of Treatment-naïve Neuroblastoma - A Mortality Experience from a Tertiary Medical Institution |
| title_full_unstemmed | Unexpected Tumor Rupture in a Case of Treatment-naïve Neuroblastoma - A Mortality Experience from a Tertiary Medical Institution |
| title_short | Unexpected Tumor Rupture in a Case of Treatment-naïve Neuroblastoma - A Mortality Experience from a Tertiary Medical Institution |
| title_sort | unexpected tumor rupture in a case of treatment naive neuroblastoma a mortality experience from a tertiary medical institution |
| topic | mortality neuroblastoma oncology pediatrics |
| url | https://jpediatricacademy.com/index.php/jpa/article/view/254 |
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