Evaluation of rapid pleurodesis technique in patients with malignant pleural effusion

Abstract Background The objective of this study is to see whether a rapid method of pleurodesis is superior to the standard protocol in patients with symptomatic malignant pleural effusion. Patients and methods This is a prospective, randomized control study that was held in Ain-Shams University Hos...

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Main Authors: Muhammed A. Farrag, Haytham S. Diab, Muhammed R. Abd Al Aziz Taha
Format: Article
Language:English
Published: SpringerOpen 2019-07-01
Series:The Egyptian Journal of Bronchology
Subjects:
Online Access:http://link.springer.com/article/10.4103/ejb.ejb_102_17
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author Muhammed A. Farrag
Haytham S. Diab
Muhammed R. Abd Al Aziz Taha
author_facet Muhammed A. Farrag
Haytham S. Diab
Muhammed R. Abd Al Aziz Taha
author_sort Muhammed A. Farrag
collection DOAJ
description Abstract Background The objective of this study is to see whether a rapid method of pleurodesis is superior to the standard protocol in patients with symptomatic malignant pleural effusion. Patients and methods This is a prospective, randomized control study that was held in Ain-Shams University Hospitals and included 30 patients diagnosed with malignant pleural effusion. Thirty patients who had been diagnosed with malignant pleural effusion histologically and/or cytologically were assessed and they were divided into two groups. Group A: 10 patients submitted to the standard pleurodesis technique using 24 or 28 F thoracotomy tube. Group B: 20 patients submitted to the rapid pleurodesis technique using pigtail (12 F). Pleurodesis was done by vibramycin and follow up of the patients was done with chest radiography at 1, 3, and 6 months after pleurodesis. Results There was no statistically significant difference in the demographic features, site of the primary tumor, disease characteristics, and response rates in any evaluation period in both groups. However, the number of days of drainage and hospitalization were significantly lower in the second group. Conclusion This new pleurodesis method provided a shorter hospital stay resulting in superior cost-effectiveness and palliation without sacrificing the efficacy of pleurodesis.
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spelling doaj.art-16eceba5b3844dbc9b2840159cbef3bd2022-12-21T18:30:16ZengSpringerOpenThe Egyptian Journal of Bronchology1687-84262314-85512019-07-0113337738110.4103/ejb.ejb_102_17Evaluation of rapid pleurodesis technique in patients with malignant pleural effusionMuhammed A. Farrag0Haytham S. Diab1Muhammed R. Abd Al Aziz Taha2Department of Chest Diseases, Pulmonology and Respiratory Intensive Care Unit, Faculty of medicine, Ain Shams UniversityDepartment of Chest Diseases, Pulmonology and Respiratory Intensive Care Unit, Faculty of medicine, Ain Shams UniversityDepartment of Chest Diseases, Pulmonology and Respiratory Intensive Care Unit, Faculty of medicine, Ain Shams UniversityAbstract Background The objective of this study is to see whether a rapid method of pleurodesis is superior to the standard protocol in patients with symptomatic malignant pleural effusion. Patients and methods This is a prospective, randomized control study that was held in Ain-Shams University Hospitals and included 30 patients diagnosed with malignant pleural effusion. Thirty patients who had been diagnosed with malignant pleural effusion histologically and/or cytologically were assessed and they were divided into two groups. Group A: 10 patients submitted to the standard pleurodesis technique using 24 or 28 F thoracotomy tube. Group B: 20 patients submitted to the rapid pleurodesis technique using pigtail (12 F). Pleurodesis was done by vibramycin and follow up of the patients was done with chest radiography at 1, 3, and 6 months after pleurodesis. Results There was no statistically significant difference in the demographic features, site of the primary tumor, disease characteristics, and response rates in any evaluation period in both groups. However, the number of days of drainage and hospitalization were significantly lower in the second group. Conclusion This new pleurodesis method provided a shorter hospital stay resulting in superior cost-effectiveness and palliation without sacrificing the efficacy of pleurodesis.http://link.springer.com/article/10.4103/ejb.ejb_102_17malignant pleural effusionrapid pleurodesisvibramycin
spellingShingle Muhammed A. Farrag
Haytham S. Diab
Muhammed R. Abd Al Aziz Taha
Evaluation of rapid pleurodesis technique in patients with malignant pleural effusion
The Egyptian Journal of Bronchology
malignant pleural effusion
rapid pleurodesis
vibramycin
title Evaluation of rapid pleurodesis technique in patients with malignant pleural effusion
title_full Evaluation of rapid pleurodesis technique in patients with malignant pleural effusion
title_fullStr Evaluation of rapid pleurodesis technique in patients with malignant pleural effusion
title_full_unstemmed Evaluation of rapid pleurodesis technique in patients with malignant pleural effusion
title_short Evaluation of rapid pleurodesis technique in patients with malignant pleural effusion
title_sort evaluation of rapid pleurodesis technique in patients with malignant pleural effusion
topic malignant pleural effusion
rapid pleurodesis
vibramycin
url http://link.springer.com/article/10.4103/ejb.ejb_102_17
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