Gut microbiota and autism
Introduction: Autism spectrum disorders (ASD) constitutes a group of brain developmental disorders and is characterized by difficulty with social communication and restricted, repetitive patterns of behavior, interest, or activities. ASD has no clear etiology and research is still ongoing to find it...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2019-09-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | http://www.ojs.ukw.edu.pl/index.php/johs/article/view/7380 |
| _version_ | 1828517294012104704 |
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| author | Grzegorz Boreński Magdalena Wójcik Julita Poleszak Przemysław Szabat Marta Szabat Joanna Milanowska |
| author_facet | Grzegorz Boreński Magdalena Wójcik Julita Poleszak Przemysław Szabat Marta Szabat Joanna Milanowska |
| author_sort | Grzegorz Boreński |
| collection | DOAJ |
| description | Introduction: Autism spectrum disorders (ASD) constitutes a group of brain developmental disorders and is characterized by difficulty with social communication and restricted, repetitive patterns of behavior, interest, or activities. ASD has no clear etiology and research is still ongoing to find it. Gut microbiota seems to have significant impact on the development of autism.
The aim of the study: The purpose of this systemic review was to collect and analyse available data about the role of gut microbiota and new methods of treatment of ASD.
Material and method: Standard criteria were used to review the literature data. The search of articles in the PubMed and Google Scholar database was carried out using the following keywords: autism spectrum disorder, gut microbiota, probiotics.
Description of the state of knowledge: In the studies we can found that symptoms from gastrointestinal tract occur more often in patients with ASD. Many studies confirm alterations in gut microbiota accompanying autism. The general changes are imbalance between Bacteroidetes and Firmicutes phyla, increased population of Sutterella and higher level of cultured Clostridium species in the feces. Researchers try to find a reason of these microbiota changes and the main cause they indicate is using antibiotics. Restoration of microbial balance in the colon, for instance by probiotics or microbiota transfer therapy may have beneficial effect on treatment of ASD.
Summary: Complicated relationship between gut microbiota and brain needs more studies, but at that point we can find its association with autism and ASD and also with anorexia nervosa, depression and other mood disorders and GI diseases. Among currently available methods of treatment we can distinguish behavioural treatment, pharmacological approach (risperidone and aripiprazole) and complementary and alternative medicine therapies. Understanding the impact of microbiota on autism opens up new paths of treatment, for instance probiotics, fecal microbiota transplantation or microbiota transfer therapy. Although, there is a great need for more researches of their efficacy. |
| first_indexed | 2024-12-11T18:39:33Z |
| format | Article |
| id | doaj.art-16ee2a876c3e43a095f25fc56391cd1d |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-12-11T18:39:33Z |
| publishDate | 2019-09-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-16ee2a876c3e43a095f25fc56391cd1d2022-12-22T00:54:39ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062019-09-019920421210.5281/zenodo.33953206486Gut microbiota and autismGrzegorz Boreński0Magdalena Wójcik1Julita Poleszak2Przemysław Szabat3Marta Szabat4Joanna Milanowska5Student Science Club at the Department of Applied Psychology, Medical University of LublinStudent Science Club at the Department of Applied Psychology, Medical University of LublinStudent Science Club at the Department of Applied Psychology, Medical University of LublinStudent Science Club at the Department of Applied Psychology, Medical University of LublinStudent Science Club at the Department of Applied Psychology, Medical University of LublinDepartment of Applied Psychology, Medical University of LublinIntroduction: Autism spectrum disorders (ASD) constitutes a group of brain developmental disorders and is characterized by difficulty with social communication and restricted, repetitive patterns of behavior, interest, or activities. ASD has no clear etiology and research is still ongoing to find it. Gut microbiota seems to have significant impact on the development of autism. The aim of the study: The purpose of this systemic review was to collect and analyse available data about the role of gut microbiota and new methods of treatment of ASD. Material and method: Standard criteria were used to review the literature data. The search of articles in the PubMed and Google Scholar database was carried out using the following keywords: autism spectrum disorder, gut microbiota, probiotics. Description of the state of knowledge: In the studies we can found that symptoms from gastrointestinal tract occur more often in patients with ASD. Many studies confirm alterations in gut microbiota accompanying autism. The general changes are imbalance between Bacteroidetes and Firmicutes phyla, increased population of Sutterella and higher level of cultured Clostridium species in the feces. Researchers try to find a reason of these microbiota changes and the main cause they indicate is using antibiotics. Restoration of microbial balance in the colon, for instance by probiotics or microbiota transfer therapy may have beneficial effect on treatment of ASD. Summary: Complicated relationship between gut microbiota and brain needs more studies, but at that point we can find its association with autism and ASD and also with anorexia nervosa, depression and other mood disorders and GI diseases. Among currently available methods of treatment we can distinguish behavioural treatment, pharmacological approach (risperidone and aripiprazole) and complementary and alternative medicine therapies. Understanding the impact of microbiota on autism opens up new paths of treatment, for instance probiotics, fecal microbiota transplantation or microbiota transfer therapy. Although, there is a great need for more researches of their efficacy.http://www.ojs.ukw.edu.pl/index.php/johs/article/view/7380autism spectrum disordergut microbiotaprobiotics |
| spellingShingle | Grzegorz Boreński Magdalena Wójcik Julita Poleszak Przemysław Szabat Marta Szabat Joanna Milanowska Gut microbiota and autism Journal of Education, Health and Sport autism spectrum disorder gut microbiota probiotics |
| title | Gut microbiota and autism |
| title_full | Gut microbiota and autism |
| title_fullStr | Gut microbiota and autism |
| title_full_unstemmed | Gut microbiota and autism |
| title_short | Gut microbiota and autism |
| title_sort | gut microbiota and autism |
| topic | autism spectrum disorder gut microbiota probiotics |
| url | http://www.ojs.ukw.edu.pl/index.php/johs/article/view/7380 |
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