Novel amide-functionalized chloramphenicol base bifunctional organocatalysts for enantioselective alcoholysis of meso-cyclic anhydrides

Novel amide-functionalized chloramphenicol base bifunctional organocatalysts for enantioselective alcoholysis of meso-cyclic anhydrides

A family of novel chloramphenicol base-amide organocatalysts possessing a NH functionality at C-1 position as monodentate hydrogen bond donor were developed and evaluated for enantioselective organocatalytic alcoholysis of meso-cyclic anhydrides. These structural diversified organocatalysts were fou...

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Bibliographic Details
Main Authors: Lingjun Xu, Shuwen Han, Linjie Yan, Haifeng Wang, Haihui Peng, Fener Chen
Format: Article
Language:English
Published: Beilstein-Institut 2018-01-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
alcoholysis desymmetrization
bifunctional organocatalysis
chloramphenicol base
Online Access:https://doi.org/10.3762/bjoc.14.19

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