Preoperative Platelet-Lymphocyte Ratio as a Prognostic Factor of Epithelial Ovarian Cancer

Objective: To determine whether platelet-lymphocyte ratio can be a prognostic factor for epithelial ovarian cancer. Methods: This study was a retrospective cohort with analytical design, conducted in the Department of Obstetrics and Gynecology of Prof. Dr. R.D. Kandou Manado General Hospital from J...

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Bibliographic Details
Main Authors: Johan Winata, Bismarck Joel Laihad, Frank Mitchell Marvel Wagey
Format: Article
Language:English
Published: Indonesian Society of Obstetrics and Gynecology 2023-05-01
Series:Indonesian Journal of Obstetrics and Gynecology
Online Access:https://inajog.com/index.php/journal/article/view/1738
Description
Summary:Objective: To determine whether platelet-lymphocyte ratio can be a prognostic factor for epithelial ovarian cancer. Methods: This study was a retrospective cohort with analytical design, conducted in the Department of Obstetrics and Gynecology of Prof. Dr. R.D. Kandou Manado General Hospital from January – November 2020. The subjects were all patients with epithelial ovarian cancer who met the inclusion and exclusion criteria. Data analysis was conducted with Chi-square test. Results: 35 subjects were included in this study. Most subjects were 40-50 years and had a platelet-lymphocyte ratio of above 200. The mean platelet-lymphocyte ratio of the subjects with epithelial ovarian cancer was 244.663 +- 130.0234. Chi-square test showed a significant association between platelet-lymphocyte ratio and the ovarian cancer relapse (X2 = 14.464 p = 0.000) with RR=4.0 Conclusion: There was a significant difference between platelet-lymphocyte ratio and the ovarian cancer relapse. Keywords: epithelial ovarian cancer, inflammatory marker, platelet-lymphocyte ratio, prognosis.
ISSN:2338-6401
2338-7335