Neuroprotective effects of tenuigenin on neurobehavior, oxidative stress, and tau hyperphosphorylation induced by intracerebroventricular streptozotocin in rats
BACKGROUND: Tenuigenin (TEN), a major active component of the Chinese herb Polygala tenuifolia root, has been used to improve memory and cognitive function in Traditional Chinese Medicine for centuries. PURPOSE: The present study was designed to explore the possible neuroprotective effect of TEN on...
Main Authors: | Xiao-Bo Huang, Yu-Jing Chen, Wen-Qiang Chen, Ning-Qun Wang, Xi-Ling Wu, Yan Liu |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2018-01-01
|
Series: | Brain Circulation |
Subjects: | |
Online Access: | http://www.braincirculation.org/article.asp?issn=2394-8108;year=2018;volume=4;issue=1;spage=24;epage=32;aulast=Huang |
Similar Items
-
Hyperphosphorylation of Tau Protein in Hippocampus of Central Insulin-Resistant Rats is Associated with Cognitive Impairment
by: Dantao Peng, et al.
Published: (2013-11-01) -
Hyperphosphorylation-induced tau oligomers
by: Khalid eIqbal, et al.
Published: (2013-08-01) -
Combined application of tenuigenin and β-asarone improved the efficacy of memantine in treating moderate-to-severe Alzheimer’s disease
by: Chang W, et al.
Published: (2018-03-01) -
Surfen and oxalyl surfen decrease tau hyperphosphorylation and mitigate neuron deficits in vivo in a zebrafish model of tauopathy
by: Seyedeh Maryam Alavi Naini, et al.
Published: (2018-03-01) -
Torpor induces reversible tau hyperphosphorylation and accumulation in mice expressing human tau
by: C. F. de Veij Mestdagh, et al.
Published: (2024-06-01)