Effect of trace copper on the microstructure, corrosion behavior and biological properties of biodegradable Mg–2Zn-1Gd-0.5Zr alloy
The biodegradable Mg–2Zn-1Gd-0.5Zr-xCu (x = 0, 0.1, 0.3, 0.5 wt.%) alloys are prepared to evaluate their microstructures, corrosion behavior, biocompatibility and antimicrobial properties. When the Cu element adds to the alloys, the new MgZnCu phase generates in the alloys in addition to the MgZn2 p...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-05-01
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| Series: | Journal of Materials Research and Technology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2238785422003581 |
| _version_ | 1818315258533511168 |
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| author | Mingliang Qiao Jianchun Sha Siqi Yin Wenhong Liu Zhong Zhao Jianzhong Cui Zhiqiang Zhang |
| author_facet | Mingliang Qiao Jianchun Sha Siqi Yin Wenhong Liu Zhong Zhao Jianzhong Cui Zhiqiang Zhang |
| author_sort | Mingliang Qiao |
| collection | DOAJ |
| description | The biodegradable Mg–2Zn-1Gd-0.5Zr-xCu (x = 0, 0.1, 0.3, 0.5 wt.%) alloys are prepared to evaluate their microstructures, corrosion behavior, biocompatibility and antimicrobial properties. When the Cu element adds to the alloys, the new MgZnCu phase generates in the alloys in addition to the MgZn2 phase, W–Mg3Gd2Zn3 phase and I–Mg3Gd6Zn phase. With the Cu content increases, the grains become finer. Meanwhile, the shape of the MgZnCu phase transforms from spherical and elongated into the reticular. The grain boundary, the reticular W–Mg3Gd2Zn3 phase and the MgZnCu phase act as physical barriers to hinder the spread of corrosion. The generation of Ca–P compounds and the formation of dense oxides further improve the corrosion resistance of the alloys. Meanwhile, an increase in the content of the second phase and a change in the morphology of the MgZnCu phase also enhance galvanic corrosion, which reduces the corrosion resistance of the alloys. The corrosion rate of the Mg–2Zn-1Gd-0.5Zr-0.1Cu alloy is 0.47 ± 0.05 mm/year, and its degradation rate is much lower than that of the other Cu-containing alloys. Mg–2Zn-1Gd-0.5Zr-0.1Cu alloy has no cytotoxicity to MC3T3-E1 in the biocompatibility tests and shows good antibacterial properties in the antimicrobial experiments. In general, the Mg–2Zn-1Gd-0.5Zr-0.1Cu alloy is considered as the potential biodegradable antimicrobial biomaterial for bone implants. |
| first_indexed | 2024-12-13T09:02:41Z |
| format | Article |
| id | doaj.art-16f354b1fc7b4dfabe1d7b0f269f1871 |
| institution | Directory Open Access Journal |
| issn | 2238-7854 |
| language | English |
| last_indexed | 2024-12-13T09:02:41Z |
| publishDate | 2022-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Materials Research and Technology |
| spelling | doaj.art-16f354b1fc7b4dfabe1d7b0f269f18712022-12-21T23:53:08ZengElsevierJournal of Materials Research and Technology2238-78542022-05-011816071622Effect of trace copper on the microstructure, corrosion behavior and biological properties of biodegradable Mg–2Zn-1Gd-0.5Zr alloyMingliang Qiao0Jianchun Sha1Siqi Yin2Wenhong Liu3Zhong Zhao4Jianzhong Cui5Zhiqiang Zhang6Key Lab of Electromagnetic Processing of Materials, Ministry of Education, Northeastern University, Shenyang, 110819, PR China; Engineering Research Center of Advanced Materials Preparing Technology, Ministry of Education, Northeastern University, Shenyang, 110819, PR ChinaKey Lab of Electromagnetic Processing of Materials, Ministry of Education, Northeastern University, Shenyang, 110819, PR China; Engineering Research Center of Advanced Materials Preparing Technology, Ministry of Education, Northeastern University, Shenyang, 110819, PR ChinaSchool of Mechanical Engineering, Dalian Jiaotong University, Dalian, 116028, PR ChinaCollege of Information Science and Engineering, Northeastern University, Shenyang, 110819, PR ChinaState Key Laboratory of Rolling and Automation, Northeastern University, Shenyang, 110819, Liaoning, PR ChinaKey Lab of Electromagnetic Processing of Materials, Ministry of Education, Northeastern University, Shenyang, 110819, PR China; Engineering Research Center of Advanced Materials Preparing Technology, Ministry of Education, Northeastern University, Shenyang, 110819, PR ChinaKey Lab of Electromagnetic Processing of Materials, Ministry of Education, Northeastern University, Shenyang, 110819, PR China; Engineering Research Center of Advanced Materials Preparing Technology, Ministry of Education, Northeastern University, Shenyang, 110819, PR China; Corresponding author.The biodegradable Mg–2Zn-1Gd-0.5Zr-xCu (x = 0, 0.1, 0.3, 0.5 wt.%) alloys are prepared to evaluate their microstructures, corrosion behavior, biocompatibility and antimicrobial properties. When the Cu element adds to the alloys, the new MgZnCu phase generates in the alloys in addition to the MgZn2 phase, W–Mg3Gd2Zn3 phase and I–Mg3Gd6Zn phase. With the Cu content increases, the grains become finer. Meanwhile, the shape of the MgZnCu phase transforms from spherical and elongated into the reticular. The grain boundary, the reticular W–Mg3Gd2Zn3 phase and the MgZnCu phase act as physical barriers to hinder the spread of corrosion. The generation of Ca–P compounds and the formation of dense oxides further improve the corrosion resistance of the alloys. Meanwhile, an increase in the content of the second phase and a change in the morphology of the MgZnCu phase also enhance galvanic corrosion, which reduces the corrosion resistance of the alloys. The corrosion rate of the Mg–2Zn-1Gd-0.5Zr-0.1Cu alloy is 0.47 ± 0.05 mm/year, and its degradation rate is much lower than that of the other Cu-containing alloys. Mg–2Zn-1Gd-0.5Zr-0.1Cu alloy has no cytotoxicity to MC3T3-E1 in the biocompatibility tests and shows good antibacterial properties in the antimicrobial experiments. In general, the Mg–2Zn-1Gd-0.5Zr-0.1Cu alloy is considered as the potential biodegradable antimicrobial biomaterial for bone implants.http://www.sciencedirect.com/science/article/pii/S2238785422003581Mg alloyCopperMicrostructureBiological propertiesCorrosion |
| spellingShingle | Mingliang Qiao Jianchun Sha Siqi Yin Wenhong Liu Zhong Zhao Jianzhong Cui Zhiqiang Zhang Effect of trace copper on the microstructure, corrosion behavior and biological properties of biodegradable Mg–2Zn-1Gd-0.5Zr alloy Journal of Materials Research and Technology Mg alloy Copper Microstructure Biological properties Corrosion |
| title | Effect of trace copper on the microstructure, corrosion behavior and biological properties of biodegradable Mg–2Zn-1Gd-0.5Zr alloy |
| title_full | Effect of trace copper on the microstructure, corrosion behavior and biological properties of biodegradable Mg–2Zn-1Gd-0.5Zr alloy |
| title_fullStr | Effect of trace copper on the microstructure, corrosion behavior and biological properties of biodegradable Mg–2Zn-1Gd-0.5Zr alloy |
| title_full_unstemmed | Effect of trace copper on the microstructure, corrosion behavior and biological properties of biodegradable Mg–2Zn-1Gd-0.5Zr alloy |
| title_short | Effect of trace copper on the microstructure, corrosion behavior and biological properties of biodegradable Mg–2Zn-1Gd-0.5Zr alloy |
| title_sort | effect of trace copper on the microstructure corrosion behavior and biological properties of biodegradable mg 2zn 1gd 0 5zr alloy |
| topic | Mg alloy Copper Microstructure Biological properties Corrosion |
| url | http://www.sciencedirect.com/science/article/pii/S2238785422003581 |
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