Synthesis and Characterization of Process-Related Impurities of Antidiabetic Drug Linagliptin
Linagliptin, a xanthine derivative, is a highly potent, selective, long-acting and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes. During the process development of linagliptin, five new process-related impurities were detected by high performance liquid chromatography (HPL...
| Autori principali: | , , , |
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| Natura: | Articolo |
| Lingua: | English |
| Pubblicazione: |
MDPI AG
2016-08-01
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| Serie: | Molecules |
| Soggetti: | |
| Accesso online: | http://www.mdpi.com/1420-3049/21/8/1041 |