Synthesis and Characterization of Process-Related Impurities of Antidiabetic Drug Linagliptin

Linagliptin, a xanthine derivative, is a highly potent, selective, long-acting and orally bioavailable DPP-4 inhibitor for the treatment of type 2 diabetes. During the process development of linagliptin, five new process-related impurities were detected by high performance liquid chromatography (HPL...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Yiwen Huang, Xiaoqing He, Taizhi Wu, Fuli Zhang
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: MDPI AG 2016-08-01
Цуврал:Molecules
Нөхцлүүд:
Онлайн хандалт:http://www.mdpi.com/1420-3049/21/8/1041