Interrogating Plant-Microbe Interactions with Chemical Tools: Click Chemistry Reagents for Metabolic Labeling and Activity-Based Probes
Continued expansion of the chemical biology toolbox presents many new and diverse opportunities to interrogate the fundamental molecular mechanisms driving complex plant–microbe interactions. This review will examine metabolic labeling with click chemistry reagents and activity-based probes for inve...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-01-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/26/1/243 |
| _version_ | 1797542231905665024 |
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| author | Vivian S. Lin |
| author_facet | Vivian S. Lin |
| author_sort | Vivian S. Lin |
| collection | DOAJ |
| description | Continued expansion of the chemical biology toolbox presents many new and diverse opportunities to interrogate the fundamental molecular mechanisms driving complex plant–microbe interactions. This review will examine metabolic labeling with click chemistry reagents and activity-based probes for investigating the impacts of plant-associated microbes on plant growth, metabolism, and immune responses. While the majority of the studies reviewed here used chemical biology approaches to examine the effects of pathogens on plants, chemical biology will also be invaluable in future efforts to investigate mutualistic associations between beneficial microbes and their plant hosts. |
| first_indexed | 2024-03-10T13:27:45Z |
| format | Article |
| id | doaj.art-16f5aacc05d042c7b6910ddf146c5374 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T13:27:45Z |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-16f5aacc05d042c7b6910ddf146c53742023-11-21T08:32:53ZengMDPI AGMolecules1420-30492021-01-0126124310.3390/molecules26010243Interrogating Plant-Microbe Interactions with Chemical Tools: Click Chemistry Reagents for Metabolic Labeling and Activity-Based ProbesVivian S. Lin0Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99354, USAContinued expansion of the chemical biology toolbox presents many new and diverse opportunities to interrogate the fundamental molecular mechanisms driving complex plant–microbe interactions. This review will examine metabolic labeling with click chemistry reagents and activity-based probes for investigating the impacts of plant-associated microbes on plant growth, metabolism, and immune responses. While the majority of the studies reviewed here used chemical biology approaches to examine the effects of pathogens on plants, chemical biology will also be invaluable in future efforts to investigate mutualistic associations between beneficial microbes and their plant hosts.https://www.mdpi.com/1420-3049/26/1/243chemical biologyplant–microbe interactionsmetabolic labelingclick chemistrybiosensorsactivity-based probes |
| spellingShingle | Vivian S. Lin Interrogating Plant-Microbe Interactions with Chemical Tools: Click Chemistry Reagents for Metabolic Labeling and Activity-Based Probes Molecules chemical biology plant–microbe interactions metabolic labeling click chemistry biosensors activity-based probes |
| title | Interrogating Plant-Microbe Interactions with Chemical Tools: Click Chemistry Reagents for Metabolic Labeling and Activity-Based Probes |
| title_full | Interrogating Plant-Microbe Interactions with Chemical Tools: Click Chemistry Reagents for Metabolic Labeling and Activity-Based Probes |
| title_fullStr | Interrogating Plant-Microbe Interactions with Chemical Tools: Click Chemistry Reagents for Metabolic Labeling and Activity-Based Probes |
| title_full_unstemmed | Interrogating Plant-Microbe Interactions with Chemical Tools: Click Chemistry Reagents for Metabolic Labeling and Activity-Based Probes |
| title_short | Interrogating Plant-Microbe Interactions with Chemical Tools: Click Chemistry Reagents for Metabolic Labeling and Activity-Based Probes |
| title_sort | interrogating plant microbe interactions with chemical tools click chemistry reagents for metabolic labeling and activity based probes |
| topic | chemical biology plant–microbe interactions metabolic labeling click chemistry biosensors activity-based probes |
| url | https://www.mdpi.com/1420-3049/26/1/243 |
| work_keys_str_mv | AT vivianslin interrogatingplantmicrobeinteractionswithchemicaltoolsclickchemistryreagentsformetaboliclabelingandactivitybasedprobes |