Comparison of Antibacterial Efficacy of Turmeric Extract, Morinda Citrifolia and 3% Sodium Hypochlorite on Enterococcus faecalis: An In-vitro Study
Introduction: Sodium hypochlorite (NaOCl), the most commonly used irrigant, has many potential properties like its unique ability to dissolve pulp tissue, excellent antimicrobial activity, but has a cytotoxic effect when injected into periapical tissues. It is also known to produce allergic react...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2016-10-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/8650/19718_CE(EK)_F(AK)_PF1(NEAK)_PFA(AK)_PF2(EKAK).pdf |
| Summary: | Introduction: Sodium hypochlorite (NaOCl), the most commonly used irrigant, has many potential properties like its unique
ability to dissolve pulp tissue, excellent antimicrobial activity,
but has a cytotoxic effect when injected into periapical tissues.
It is also known to produce allergic reactions, foul smell and
taste, and potential for corrosion. Facultative organisms such
as Enterococcus faecalis and aerobes like Staphylococcus aureus are considered to be the most resistant species and one of
the possible causes of root canal treatment failure. So there is a
need to find an alternative to sodium hypochlorite to act against
these resistant microorganisms.
Aim: To evaluate and compare the antibacterial efficacy of
morinda citrifolia and turmeric extract with 3% NaOCl as a root
canal irrigant, against E. faecalis and S.aureus.
Materials and Methods: The antimicrobial efficacy was assessed in vitro using agar well diffusion method. Agar plates
were prepared using Brain-Heart Infusion (BHI) agar. Cultures
of E.faecalis and S.aureus were grown in nutrient broth at 37°C.
Plates were incubated for 24 hours at 37°C and microbial zones
of inhibition were recorded. Statistical analysis was performed
using ANOVA.
Results: NaOCl (3%) showed larger zones of inhibition than
herbal irrigants against both the microorganisms. Among the
herbal irrigants, morinda citrifolia showed larger zones of inhibition than turmeric hydro-alcoholic extract and turmeric water
extract which was statistically significant (p<0.05).
Conclusion: NaOCl (3%) showed maximum antibacterial activity against E. faecalis, followed by morinda citrifolia and turmeric
extracts. Considering the potential for undesirable properties of
NaOCl, use of herbal alternatives in endodontics might prove to
be advantageous. |
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| ISSN: | 2249-782X 0973-709X |