Adenosine-Assisted Management of Intracranial Aneurysm
Cerebral aneurysms can be complex and variable in size, position, and morphology, resulting in difficult surgical exposure and secure clip placement. They have a high mortality rate when ruptured, and though endovascular techniques have emerged to tackle this, surgical clip ligation remains the pref...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
2019-02-01
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| Series: | Journal of Neuroanaesthesiology and Critical Care |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1676555 |
| _version_ | 1818969657174917120 |
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| author | Bhoomika Thakore Shwetal Goraksha Joseph N. Monteiro |
| author_facet | Bhoomika Thakore Shwetal Goraksha Joseph N. Monteiro |
| author_sort | Bhoomika Thakore |
| collection | DOAJ |
| description | Cerebral aneurysms can be complex and variable in size, position, and morphology, resulting in difficult surgical exposure and secure clip placement. They have a high mortality rate when ruptured, and though endovascular techniques have emerged to tackle this, surgical clip ligation remains the preferred modality for some aneurysms. Various techniques that help the surgeon dissect the aneurysmal dome and apply the clip are temporary clip ligation of proximal vessels, deep hypothermic circulatory arrest, and balloon suction decompression. All of them require significant logistics and result in increased morbidity and mortality. Adenosine is a suitable alternative for inducing a temporary flow arrest, causing a short period of controlled hypotension. Its rapid onset and offset property along with low incidence of adverse events makes it an ideal agent in this regard. We present here a review on its use, contraindications, safety profile, and future applications. |
| first_indexed | 2024-12-20T14:24:04Z |
| format | Article |
| id | doaj.art-16fb176f56d74536ad69fb5a3831a7d2 |
| institution | Directory Open Access Journal |
| issn | 2348-0548 2348-926X |
| language | English |
| last_indexed | 2024-12-20T14:24:04Z |
| publishDate | 2019-02-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Journal of Neuroanaesthesiology and Critical Care |
| spelling | doaj.art-16fb176f56d74536ad69fb5a3831a7d22022-12-21T19:37:51ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Neuroanaesthesiology and Critical Care2348-05482348-926X2019-02-01060101301710.1055/s-0038-1676555Adenosine-Assisted Management of Intracranial AneurysmBhoomika Thakore0Shwetal Goraksha1Joseph N. Monteiro2Neuroanaesthesia Program, Department of Anaesthesiology, P. D. Hinduja Hospital, Mumbai, Maharashtra, IndiaNeuroanaesthesia Program, Department of Anaesthesiology, P. D. Hinduja Hospital, Mumbai, Maharashtra, IndiaNeuroanaesthesia Program, Department of Anaesthesiology, P. D. Hinduja Hospital, Mumbai, Maharashtra, IndiaCerebral aneurysms can be complex and variable in size, position, and morphology, resulting in difficult surgical exposure and secure clip placement. They have a high mortality rate when ruptured, and though endovascular techniques have emerged to tackle this, surgical clip ligation remains the preferred modality for some aneurysms. Various techniques that help the surgeon dissect the aneurysmal dome and apply the clip are temporary clip ligation of proximal vessels, deep hypothermic circulatory arrest, and balloon suction decompression. All of them require significant logistics and result in increased morbidity and mortality. Adenosine is a suitable alternative for inducing a temporary flow arrest, causing a short period of controlled hypotension. Its rapid onset and offset property along with low incidence of adverse events makes it an ideal agent in this regard. We present here a review on its use, contraindications, safety profile, and future applications.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1676555adenosinecerebral aneurysmflow arrest |
| spellingShingle | Bhoomika Thakore Shwetal Goraksha Joseph N. Monteiro Adenosine-Assisted Management of Intracranial Aneurysm Journal of Neuroanaesthesiology and Critical Care adenosine cerebral aneurysm flow arrest |
| title | Adenosine-Assisted Management of Intracranial Aneurysm |
| title_full | Adenosine-Assisted Management of Intracranial Aneurysm |
| title_fullStr | Adenosine-Assisted Management of Intracranial Aneurysm |
| title_full_unstemmed | Adenosine-Assisted Management of Intracranial Aneurysm |
| title_short | Adenosine-Assisted Management of Intracranial Aneurysm |
| title_sort | adenosine assisted management of intracranial aneurysm |
| topic | adenosine cerebral aneurysm flow arrest |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1676555 |
| work_keys_str_mv | AT bhoomikathakore adenosineassistedmanagementofintracranialaneurysm AT shwetalgoraksha adenosineassistedmanagementofintracranialaneurysm AT josephnmonteiro adenosineassistedmanagementofintracranialaneurysm |