Trajectories of Heart Activity Across Infancy to Early Childhood Differentially Predict Autism and Anxiety Symptoms in Fragile X Syndrome

Trajectories of Heart Activity Across Infancy to Early Childhood Differentially Predict Autism and Anxiety Symptoms in Fragile X Syndrome

Background: Fragile X syndrome (FXS) is a monogenic disorder characterized by high rates of autism spectrum disorder (ASD) and anxiety. A longstanding “hyperarousal hypothesis” in FXS has argued that ANS dysfunction underpins many symptoms of FXS. However, the developmental onset and trajectory of A...

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Bibliographic Details
Main Authors: Abigail Hogan, Erin Hunt, Kayla Smith, Conner Black, Katherine Bangert, Jessica Klusek, Jane Roberts
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Psychiatry
Subjects:
autonomic nervous system
respiratory sinus arrhythmia
interbeat interval
hyperarousal
fragile X syndrome
autism spectrum disorder
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.727559/full

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