Polymer-Based Scaffolds for Soft-Tissue Engineering

Biomaterials have been used since ancient times. However, it was not until the late 1960s when their development prospered, increasing the research on them. In recent years, the study of biomaterials has focused mainly on tissue regeneration, requiring a biomaterial that can support cells during the...

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Main Authors: Victor Perez-Puyana, Mercedes Jiménez-Rosado, Alberto Romero, Antonio Guerrero
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/12/7/1566
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author Victor Perez-Puyana
Mercedes Jiménez-Rosado
Alberto Romero
Antonio Guerrero
author_facet Victor Perez-Puyana
Mercedes Jiménez-Rosado
Alberto Romero
Antonio Guerrero
author_sort Victor Perez-Puyana
collection DOAJ
description Biomaterials have been used since ancient times. However, it was not until the late 1960s when their development prospered, increasing the research on them. In recent years, the study of biomaterials has focused mainly on tissue regeneration, requiring a biomaterial that can support cells during their growth and fulfill the function of the replaced tissue until its regeneration. These materials, called scaffolds, have been developed with a wide variety of materials and processes, with the polymer ones being the most advanced. For this reason, the need arises for a review that compiles the techniques most used in the development of polymer-based scaffolds. This review has focused on three of the most used techniques: freeze-drying, electrospinning and 3D printing, focusing on current and future trends. In addition, the advantages and disadvantages of each of them have been compared.
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spelling doaj.art-1702c6e88a634d36860313996d3d0df32023-11-20T06:49:43ZengMDPI AGPolymers2073-43602020-07-01127156610.3390/polym12071566Polymer-Based Scaffolds for Soft-Tissue EngineeringVictor Perez-Puyana0Mercedes Jiménez-Rosado1Alberto Romero2Antonio Guerrero3Departamento de Ingeniería Química, Facultad de Química, Universidad de Sevilla, 41012 Sevilla, SpainDepartamento de Ingeniería Química, Escuela Politécnica Superior, Universidad de Sevilla, 41011 Sevilla, SpainDepartamento de Ingeniería Química, Facultad de Química, Universidad de Sevilla, 41012 Sevilla, SpainDepartamento de Ingeniería Química, Escuela Politécnica Superior, Universidad de Sevilla, 41011 Sevilla, SpainBiomaterials have been used since ancient times. However, it was not until the late 1960s when their development prospered, increasing the research on them. In recent years, the study of biomaterials has focused mainly on tissue regeneration, requiring a biomaterial that can support cells during their growth and fulfill the function of the replaced tissue until its regeneration. These materials, called scaffolds, have been developed with a wide variety of materials and processes, with the polymer ones being the most advanced. For this reason, the need arises for a review that compiles the techniques most used in the development of polymer-based scaffolds. This review has focused on three of the most used techniques: freeze-drying, electrospinning and 3D printing, focusing on current and future trends. In addition, the advantages and disadvantages of each of them have been compared.https://www.mdpi.com/2073-4360/12/7/1566freeze-dryingelectrospinning3D printingbioactive scaffoldstissue engineering
spellingShingle Victor Perez-Puyana
Mercedes Jiménez-Rosado
Alberto Romero
Antonio Guerrero
Polymer-Based Scaffolds for Soft-Tissue Engineering
Polymers
freeze-drying
electrospinning
3D printing
bioactive scaffolds
tissue engineering
title Polymer-Based Scaffolds for Soft-Tissue Engineering
title_full Polymer-Based Scaffolds for Soft-Tissue Engineering
title_fullStr Polymer-Based Scaffolds for Soft-Tissue Engineering
title_full_unstemmed Polymer-Based Scaffolds for Soft-Tissue Engineering
title_short Polymer-Based Scaffolds for Soft-Tissue Engineering
title_sort polymer based scaffolds for soft tissue engineering
topic freeze-drying
electrospinning
3D printing
bioactive scaffolds
tissue engineering
url https://www.mdpi.com/2073-4360/12/7/1566
work_keys_str_mv AT victorperezpuyana polymerbasedscaffoldsforsofttissueengineering
AT mercedesjimenezrosado polymerbasedscaffoldsforsofttissueengineering
AT albertoromero polymerbasedscaffoldsforsofttissueengineering
AT antonioguerrero polymerbasedscaffoldsforsofttissueengineering