Hypertensive Emergency In UMOD-Related Autosomal Dominant Tubulointerstitial Kidney Disease

Hypertensive emergency is characterized by an acute elevation in blood pressure with evidence of impending or progressive acute target organ damage. Management relies mainly on intravenous medications guided by the type of target-organ damage, but there is considerable variability in practice regard...

Full description

Bibliographic Details
Main Authors: Talha Chaudhry, Sunil Sapru
Format: Article
Language:English
Published: Department of Medicine, Warren Alpert Medical School at Brown University 2022-10-01
Series:Brown Journal of Hospital Medicine
Online Access:https://bhm.scholasticahq.com/article/38580-hypertensive-emergency-in-umod-related-autosomal-dominant-tubulointerstitial-kidney-disease
Description
Summary:Hypertensive emergency is characterized by an acute elevation in blood pressure with evidence of impending or progressive acute target organ damage. Management relies mainly on intravenous medications guided by the type of target-organ damage, but there is considerable variability in practice regarding the choice of medications and optimal therapy. Such variables include the choice of agent and the blood pressure goal, but also underlying medical conditions. We report a case of hypertensive emergency in a 39-year-old-male with a rare genetic condition, UMOD-related autosomal dominant tubulointerstitial kidney disease which gave rise to adolescent gout, worsening kidney function over decades and treatment-resistant hypertension.
ISSN:2831-5553