Retrograde ejaculation as an initial presenting symptom of type 2 diabetes mellitus: a case report and literature review
Retrograde ejaculation (RE), known as one of the late complications of diabetes mellitus, is rarely a presenting symptom in the diagnosis of diabetes. A 30-year-old male presented with a progressive decline in ejaculate over 2-month. Lab results revealed a high random blood glucose level (425 mg/dL)...
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| Format: | Article |
| Language: | English |
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MRE Press
2022-02-01
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| Series: | Journal of Men's Health |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/JOMH/18/3/10.31083/jomh.2021.114 |
| _version_ | 1827359306020814848 |
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| author | Yu-Shan Mao Ning-Jun Fang Zhi-Ren Sheng Yi-Feng Mai |
| author_facet | Yu-Shan Mao Ning-Jun Fang Zhi-Ren Sheng Yi-Feng Mai |
| author_sort | Yu-Shan Mao |
| collection | DOAJ |
| description | Retrograde ejaculation (RE), known as one of the late complications of diabetes mellitus, is rarely a presenting symptom in the diagnosis of diabetes. A 30-year-old male presented with a progressive decline in ejaculate over 2-month. Lab results revealed a high random blood glucose level (425 mg/dL). A substantial number of sperm were found in the post-ejaculate urine specimens, confirming a diagnosis of RE. Further lab tests revealed an hemoglobin-A1c (HbA1c) of 12.7%, with negative results for antibodies to glutamic acid decarboxylase, insulin antigen-2, insulin receptor and islet cell, consistent with a diagnosis of type 2 diabetes mellitus (T2DM). Insulin glargine and oral anti-hyperglycemic agents were initiated. Also, imipramine and pseudoephedrine were prescribed for 4-week and then discontinued, as no positive effect on ejaculation was seen. At the 36-month follow-up, the patient had a normal glucose level with HbA1c <6.5%. However, RE persisted. RE is commonly seen as a late-stage complication among T2DM. We presented a rare case where RE was the first referred symptom of T2DM and RE persisted even after adequate control of glycemia. |
| first_indexed | 2024-03-08T06:26:00Z |
| format | Article |
| id | doaj.art-17052294931a475e843f533355c485e9 |
| institution | Directory Open Access Journal |
| issn | 1875-6859 |
| language | English |
| last_indexed | 2024-03-08T06:26:00Z |
| publishDate | 2022-02-01 |
| publisher | MRE Press |
| record_format | Article |
| series | Journal of Men's Health |
| spelling | doaj.art-17052294931a475e843f533355c485e92024-02-03T14:44:29ZengMRE PressJournal of Men's Health1875-68592022-02-0118305810.31083/jomh.2021.114S1875-6867(22)00290-1Retrograde ejaculation as an initial presenting symptom of type 2 diabetes mellitus: a case report and literature reviewYu-Shan Mao0Ning-Jun Fang1Zhi-Ren Sheng2Yi-Feng Mai3Department of Endocrinology, the Affiliated Hospital of Medical School, Ningbo University, 315020 Ningbo, Zhejiang, ChinaDepartment of Urology, the Affiliated Hospital of Medical School, Ningbo University, 315020 Ningbo, Zhejiang, ChinaDepartment of Endocrinology, the Affiliated Hospital of Medical School, Ningbo University, 315020 Ningbo, Zhejiang, ChinaDepartment of Endocrinology, the Affiliated Hospital of Medical School, Ningbo University, 315020 Ningbo, Zhejiang, ChinaRetrograde ejaculation (RE), known as one of the late complications of diabetes mellitus, is rarely a presenting symptom in the diagnosis of diabetes. A 30-year-old male presented with a progressive decline in ejaculate over 2-month. Lab results revealed a high random blood glucose level (425 mg/dL). A substantial number of sperm were found in the post-ejaculate urine specimens, confirming a diagnosis of RE. Further lab tests revealed an hemoglobin-A1c (HbA1c) of 12.7%, with negative results for antibodies to glutamic acid decarboxylase, insulin antigen-2, insulin receptor and islet cell, consistent with a diagnosis of type 2 diabetes mellitus (T2DM). Insulin glargine and oral anti-hyperglycemic agents were initiated. Also, imipramine and pseudoephedrine were prescribed for 4-week and then discontinued, as no positive effect on ejaculation was seen. At the 36-month follow-up, the patient had a normal glucose level with HbA1c <6.5%. However, RE persisted. RE is commonly seen as a late-stage complication among T2DM. We presented a rare case where RE was the first referred symptom of T2DM and RE persisted even after adequate control of glycemia.https://www.imrpress.com/journal/JOMH/18/3/10.31083/jomh.2021.114retrograde ejaculationtype 2 diabetes mellituscomplicationcase report |
| spellingShingle | Yu-Shan Mao Ning-Jun Fang Zhi-Ren Sheng Yi-Feng Mai Retrograde ejaculation as an initial presenting symptom of type 2 diabetes mellitus: a case report and literature review Journal of Men's Health retrograde ejaculation type 2 diabetes mellitus complication case report |
| title | Retrograde ejaculation as an initial presenting symptom of type 2 diabetes mellitus: a case report and literature review |
| title_full | Retrograde ejaculation as an initial presenting symptom of type 2 diabetes mellitus: a case report and literature review |
| title_fullStr | Retrograde ejaculation as an initial presenting symptom of type 2 diabetes mellitus: a case report and literature review |
| title_full_unstemmed | Retrograde ejaculation as an initial presenting symptom of type 2 diabetes mellitus: a case report and literature review |
| title_short | Retrograde ejaculation as an initial presenting symptom of type 2 diabetes mellitus: a case report and literature review |
| title_sort | retrograde ejaculation as an initial presenting symptom of type 2 diabetes mellitus a case report and literature review |
| topic | retrograde ejaculation type 2 diabetes mellitus complication case report |
| url | https://www.imrpress.com/journal/JOMH/18/3/10.31083/jomh.2021.114 |
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