Evaluation of central corneal thickness in patients with dry eye disease in a tertiary eye hospital in Kancheepuram
Background: Dry eye disorder is a disease mainly due to the tear insufficiency which results in eye discomfort and disturbances in vision. Dry eye also affects the ocular dimensions, especially corneal thickness. Central corneal thickness (CCT) assessment plays an important role in refractive surger...
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2022-06-01
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| Series: | Asian Journal of Medical Sciences |
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| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/40771 |
| _version_ | 1811257727404474368 |
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| author | Rubina Huda Syed Ali Nasar Waris Sankar Kumar T |
| author_facet | Rubina Huda Syed Ali Nasar Waris Sankar Kumar T |
| author_sort | Rubina Huda |
| collection | DOAJ |
| description | Background: Dry eye disorder is a disease mainly due to the tear insufficiency which results in eye discomfort and disturbances in vision. Dry eye also affects the ocular dimensions, especially corneal thickness. Central corneal thickness (CCT) assessment plays an important role in refractive surgeries and in the pre-operative assessment of other ocular surgeries.
Aims and Objectives: This study aims to assess the effect of dry eye disease (DED) on CCT with age- and gender-matched controls.
Materials and Methods: One hundred and four subjects (52 cases and 52 controls) who attended SRM Medical College and Hospital ophthalmology outpatient department were included in the study. DED was diagnosed with DEQS questionnaire, slit-lamp examination, TFBUT, and Schirmer’s test. Pachymetry was used for measuring the CCT of all subjects. Student “t”-test was used to determine the significance of difference between two means. P<0.05 was considered statistically significant.
Results: In our study, there were 60 female patients and 44 male patients. The ratio of male-to-female was 1:1.3. The CCT among cases was very low (533.19 μm±30.05) compared to controls (569.27 μm±45.56) and this difference was statistically significant (P<0.05). When subgrouped under gender, the difference in CCT among males between the two groups was statistically significant and it was highly significant among females. When the reduction in CCT among the cases was studied under different age groups, the subjects in the 41–60 years age group had a statistically highly significant difference in CCT between the two groups while it was also significant in other age groups.
Conclusion: There is a significant decrease in CCT due to DED. Pachymetry for central corneal estimation shall be included in the routine management of dry eye patients so that corneal thinning could be identified earlier and treated with artificial tears or other substitutes. |
| first_indexed | 2024-04-12T18:01:58Z |
| format | Article |
| id | doaj.art-1705e325da0543599802f6306adcfc5b |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-04-12T18:01:58Z |
| publishDate | 2022-06-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-1705e325da0543599802f6306adcfc5b2022-12-22T03:22:07ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762022-06-01136123128https://doi.org/10.3126/ajms.v13i6.40771Evaluation of central corneal thickness in patients with dry eye disease in a tertiary eye hospital in KancheepuramRubina Huda 0https://orcid.org/0000-0002-6694-1204Syed Ali Nasar Waris 1https://orcid.org/0000-0002-1178-9006Sankar Kumar T 2https://orcid.org/0000-0003-4525-8884Associate Professor, Department of Ophthalmology, SRM Medical College Hospital, Chennai, Tamil Nadu, India Associate Professor, Department of Ophthalmology, SRM Medical College Hospital, Chennai, Tamil Nadu, India Professor and Head, Department of Ophthalmology, SRM Medical College Hospital, Chennai, Tamil Nadu, India Background: Dry eye disorder is a disease mainly due to the tear insufficiency which results in eye discomfort and disturbances in vision. Dry eye also affects the ocular dimensions, especially corneal thickness. Central corneal thickness (CCT) assessment plays an important role in refractive surgeries and in the pre-operative assessment of other ocular surgeries. Aims and Objectives: This study aims to assess the effect of dry eye disease (DED) on CCT with age- and gender-matched controls. Materials and Methods: One hundred and four subjects (52 cases and 52 controls) who attended SRM Medical College and Hospital ophthalmology outpatient department were included in the study. DED was diagnosed with DEQS questionnaire, slit-lamp examination, TFBUT, and Schirmer’s test. Pachymetry was used for measuring the CCT of all subjects. Student “t”-test was used to determine the significance of difference between two means. P<0.05 was considered statistically significant. Results: In our study, there were 60 female patients and 44 male patients. The ratio of male-to-female was 1:1.3. The CCT among cases was very low (533.19 μm±30.05) compared to controls (569.27 μm±45.56) and this difference was statistically significant (P<0.05). When subgrouped under gender, the difference in CCT among males between the two groups was statistically significant and it was highly significant among females. When the reduction in CCT among the cases was studied under different age groups, the subjects in the 41–60 years age group had a statistically highly significant difference in CCT between the two groups while it was also significant in other age groups. Conclusion: There is a significant decrease in CCT due to DED. Pachymetry for central corneal estimation shall be included in the routine management of dry eye patients so that corneal thinning could be identified earlier and treated with artificial tears or other substitutes.https://www.nepjol.info/index.php/AJMS/article/view/40771central corneal thicknessdry eye diseasepachymetryschirmer’s testtear film breakup time |
| spellingShingle | Rubina Huda Syed Ali Nasar Waris Sankar Kumar T Evaluation of central corneal thickness in patients with dry eye disease in a tertiary eye hospital in Kancheepuram Asian Journal of Medical Sciences central corneal thickness dry eye disease pachymetry schirmer’s test tear film breakup time |
| title | Evaluation of central corneal thickness in patients with dry eye disease in a tertiary eye hospital in Kancheepuram |
| title_full | Evaluation of central corneal thickness in patients with dry eye disease in a tertiary eye hospital in Kancheepuram |
| title_fullStr | Evaluation of central corneal thickness in patients with dry eye disease in a tertiary eye hospital in Kancheepuram |
| title_full_unstemmed | Evaluation of central corneal thickness in patients with dry eye disease in a tertiary eye hospital in Kancheepuram |
| title_short | Evaluation of central corneal thickness in patients with dry eye disease in a tertiary eye hospital in Kancheepuram |
| title_sort | evaluation of central corneal thickness in patients with dry eye disease in a tertiary eye hospital in kancheepuram |
| topic | central corneal thickness dry eye disease pachymetry schirmer’s test tear film breakup time |
| url | https://www.nepjol.info/index.php/AJMS/article/view/40771 |
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