Establishment of a Vaginal Atrophy Rat Model and its Application in Pharmacodynamic Evaluation

Establishment of a Vaginal Atrophy Rat Model and its Application in Pharmacodynamic Evaluation

ObjectiveTo establish an animal model suitable for screening vaginal preparations, administering the corresponding drugs, and evaluating biological indicators for monitoring drug treatment effects.MethodsBilateral ovariectomy (OVX) was used to establish the disease model of rat. The estrous cycle, u...

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Bibliographic Details
Main Authors: YANG Liya, SONG Tao, HE Jialin, GUO Yiming, QI Mingkang, WANG Hanbi, WANG Huiping
Format: Article
Language:zho
Published: Editorial Office of Laboratory Animal and Comparative Medicine 2022-12-01
Series:Shiyan dongwu yu bijiao yixue
Subjects:
vaginal preparations
vaginal atrophy
ovariectomized rat model
pharmacodynamic evaluation
Online Access:https://www.slarc.org.cn/dwyx/CN/10.12300/j.issn.1674-5817.2022.014

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