Feasibility and Preliminary Effectiveness of Behavioral Activation for Patients with Cancer and Depression in Japan

Background: Though the effectiveness of behavioral activation (BA) for patients with cancer and depression were reported, there is no evidence in Japan. Objectives: This study aimed at examining the feasibility and preliminary effectiveness of BA for patients with cancer and depression in Japan. Met...

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Main Authors: Takatoshi Hirayama, Yuko Ogawa, Yuko Yanai, Akie Shindo, Moeko Tanaka, Shin-Ichi Suzuki
Format: Article
Language:English
Published: Mary Ann Liebert 2023-06-01
Series:Palliative Medicine Reports
Subjects:
Online Access:https://www.liebertpub.com/doi/full/10.1089/PMR.2023.0020
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author Takatoshi Hirayama
Yuko Ogawa
Yuko Yanai
Akie Shindo
Moeko Tanaka
Shin-Ichi Suzuki
author_facet Takatoshi Hirayama
Yuko Ogawa
Yuko Yanai
Akie Shindo
Moeko Tanaka
Shin-Ichi Suzuki
author_sort Takatoshi Hirayama
collection DOAJ
description Background: Though the effectiveness of behavioral activation (BA) for patients with cancer and depression were reported, there is no evidence in Japan. Objectives: This study aimed at examining the feasibility and preliminary effectiveness of BA for patients with cancer and depression in Japan. Methods: This pre?post study without a control group was conducted in patients with cancer and depression in Japan. The program completion rate was compared with those of previous studies to examine feasibility. To examine the preliminary effectiveness, outcomes were evaluated four times: before and immediately after the program, and two weeks and three months after the program ended. The primary outcome was the remission rate of depression using the 17-item version of the GRID Hamilton Rating Scale for Depression (HAMD17). Secondary outcomes were self-reported depression, anxiety, quality of life, changes in behavior, values, and perceived reward of activity and environmental factors. Pre- and post-program data were compared using paired-samples t-tests, and data obtained at four time points were analyzed using one-way repeated-measures analysis of variance. Results: Of the 68 patients recruited from February 2018 to January 2022, 32 were registered. The completion rate was 75% (24/32), which was similar to previous studies. The total HAMD17 score significantly improved after the program. The remission rate of depression was 62.5% (20/32), which was above the defined threshold value (30%). All but two secondary outcomes significantly improved after the program (p?<?0.05). Conclusions: The feasibility and preliminary effectiveness of BA for patients with cancer and depression in Japan were suggested. The Clinical Trial Registration number: UMIN 000036104.
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spelling doaj.art-1706ab6328294e42a9843cfebd1de1f72024-01-26T05:07:39ZengMary Ann LiebertPalliative Medicine Reports2689-28202023-06-014115016010.1089/PMR.2023.0020Feasibility and Preliminary Effectiveness of Behavioral Activation for Patients with Cancer and Depression in JapanTakatoshi HirayamaYuko OgawaYuko YanaiAkie ShindoMoeko TanakaShin-Ichi SuzukiBackground: Though the effectiveness of behavioral activation (BA) for patients with cancer and depression were reported, there is no evidence in Japan. Objectives: This study aimed at examining the feasibility and preliminary effectiveness of BA for patients with cancer and depression in Japan. Methods: This pre?post study without a control group was conducted in patients with cancer and depression in Japan. The program completion rate was compared with those of previous studies to examine feasibility. To examine the preliminary effectiveness, outcomes were evaluated four times: before and immediately after the program, and two weeks and three months after the program ended. The primary outcome was the remission rate of depression using the 17-item version of the GRID Hamilton Rating Scale for Depression (HAMD17). Secondary outcomes were self-reported depression, anxiety, quality of life, changes in behavior, values, and perceived reward of activity and environmental factors. Pre- and post-program data were compared using paired-samples t-tests, and data obtained at four time points were analyzed using one-way repeated-measures analysis of variance. Results: Of the 68 patients recruited from February 2018 to January 2022, 32 were registered. The completion rate was 75% (24/32), which was similar to previous studies. The total HAMD17 score significantly improved after the program. The remission rate of depression was 62.5% (20/32), which was above the defined threshold value (30%). All but two secondary outcomes significantly improved after the program (p?<?0.05). Conclusions: The feasibility and preliminary effectiveness of BA for patients with cancer and depression in Japan were suggested. The Clinical Trial Registration number: UMIN 000036104.https://www.liebertpub.com/doi/full/10.1089/PMR.2023.0020behavioral activationcancer patientsdepressionpsychotherapyPsycho-Oncology
spellingShingle Takatoshi Hirayama
Yuko Ogawa
Yuko Yanai
Akie Shindo
Moeko Tanaka
Shin-Ichi Suzuki
Feasibility and Preliminary Effectiveness of Behavioral Activation for Patients with Cancer and Depression in Japan
Palliative Medicine Reports
behavioral activation
cancer patients
depression
psychotherapy
Psycho-Oncology
title Feasibility and Preliminary Effectiveness of Behavioral Activation for Patients with Cancer and Depression in Japan
title_full Feasibility and Preliminary Effectiveness of Behavioral Activation for Patients with Cancer and Depression in Japan
title_fullStr Feasibility and Preliminary Effectiveness of Behavioral Activation for Patients with Cancer and Depression in Japan
title_full_unstemmed Feasibility and Preliminary Effectiveness of Behavioral Activation for Patients with Cancer and Depression in Japan
title_short Feasibility and Preliminary Effectiveness of Behavioral Activation for Patients with Cancer and Depression in Japan
title_sort feasibility and preliminary effectiveness of behavioral activation for patients with cancer and depression in japan
topic behavioral activation
cancer patients
depression
psychotherapy
Psycho-Oncology
url https://www.liebertpub.com/doi/full/10.1089/PMR.2023.0020
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