Endophytic Fungi as Novel Resources of natural Therapeutics

ABSTRACT Fungal endophytes constitute a major part of the unexplored fungal diversity. Endophytic fungi (EF) are an important source for novel, potential and active metabolites. Plant-endophyte interaction and endophyte -endophyte interactions study provide insights into mutualism and metabolite pro...

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Main Authors: Maheshwari Rajamanikyam, Varahalarao Vadlapudi, Ramars amanchy, Suryanarayana Murty Upadhyayula
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2017-08-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100430&lng=en&tlng=en
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author Maheshwari Rajamanikyam
Varahalarao Vadlapudi
Ramars amanchy
Suryanarayana Murty Upadhyayula
author_facet Maheshwari Rajamanikyam
Varahalarao Vadlapudi
Ramars amanchy
Suryanarayana Murty Upadhyayula
author_sort Maheshwari Rajamanikyam
collection DOAJ
description ABSTRACT Fungal endophytes constitute a major part of the unexplored fungal diversity. Endophytic fungi (EF) are an important source for novel, potential and active metabolites. Plant-endophyte interaction and endophyte -endophyte interactions study provide insights into mutualism and metabolite production by fungi. Bioactive compounds produced by endophytes main function are helping the host plants to resist external biotic and abiotic stress, which benefit the host survival in return. These organisms mainly consist of members of the Ascomycota, Basidiomycota, Zygomycota and Oomycota. Recently, the genome sequencing technology has emerged as one of the most efficient tools that can provide whole information of a genome in a small period of time. Endophytes are fertile ground for drug discovery. EFare considered as the hidden members of the microbial world and represent an underutilized resource for new therapeutics and compounds. Endophytes are rich source of natural products displaying broad spectrum of biological activities like anticancer, antibacterial, antiviral, immunomodulatory, antidiabetic, antioxidant, anti-arthritis and anti-inflammatory.
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spelling doaj.art-170850eabc1447efaf597a793a0023202022-12-22T03:23:31ZengInstituto de Tecnologia do Paraná (Tecpar)Brazilian Archives of Biology and Technology1678-43242017-08-0160010.1590/1678-4324-2017160542S1516-89132017000100430Endophytic Fungi as Novel Resources of natural TherapeuticsMaheshwari RajamanikyamVarahalarao VadlapudiRamars amanchySuryanarayana Murty UpadhyayulaABSTRACT Fungal endophytes constitute a major part of the unexplored fungal diversity. Endophytic fungi (EF) are an important source for novel, potential and active metabolites. Plant-endophyte interaction and endophyte -endophyte interactions study provide insights into mutualism and metabolite production by fungi. Bioactive compounds produced by endophytes main function are helping the host plants to resist external biotic and abiotic stress, which benefit the host survival in return. These organisms mainly consist of members of the Ascomycota, Basidiomycota, Zygomycota and Oomycota. Recently, the genome sequencing technology has emerged as one of the most efficient tools that can provide whole information of a genome in a small period of time. Endophytes are fertile ground for drug discovery. EFare considered as the hidden members of the microbial world and represent an underutilized resource for new therapeutics and compounds. Endophytes are rich source of natural products displaying broad spectrum of biological activities like anticancer, antibacterial, antiviral, immunomodulatory, antidiabetic, antioxidant, anti-arthritis and anti-inflammatory.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100430&lng=en&tlng=enEndophytic fungiAscomycotaNatural productsAntidiabetic
spellingShingle Maheshwari Rajamanikyam
Varahalarao Vadlapudi
Ramars amanchy
Suryanarayana Murty Upadhyayula
Endophytic Fungi as Novel Resources of natural Therapeutics
Brazilian Archives of Biology and Technology
Endophytic fungi
Ascomycota
Natural products
Antidiabetic
title Endophytic Fungi as Novel Resources of natural Therapeutics
title_full Endophytic Fungi as Novel Resources of natural Therapeutics
title_fullStr Endophytic Fungi as Novel Resources of natural Therapeutics
title_full_unstemmed Endophytic Fungi as Novel Resources of natural Therapeutics
title_short Endophytic Fungi as Novel Resources of natural Therapeutics
title_sort endophytic fungi as novel resources of natural therapeutics
topic Endophytic fungi
Ascomycota
Natural products
Antidiabetic
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100430&lng=en&tlng=en
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AT ramarsamanchy endophyticfungiasnovelresourcesofnaturaltherapeutics
AT suryanarayanamurtyupadhyayula endophyticfungiasnovelresourcesofnaturaltherapeutics