Maintenance IV Ketamine Therapy in the Fibromyalgia Patient: A Case Report

# Introduction Fibromyalgia is a complex disorder characterized by distributed and persistent pain often associated with fatigue and depression. The underlying causal agents of this dysfunction are not clear. Ketamine has been used to treat chronic pain in a variety of pain syndromes, including fib...

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Main Authors: Ruchir Gupta, Supurna Bhar
Format: Article
Language:English
Published: Open Medical Publishing 2023-11-01
Series:Health Psychology Research
Online Access:https://doi.org/10.52965/001c.89640
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author Ruchir Gupta
Supurna Bhar
author_facet Ruchir Gupta
Supurna Bhar
author_sort Ruchir Gupta
collection DOAJ
description # Introduction Fibromyalgia is a complex disorder characterized by distributed and persistent pain often associated with fatigue and depression. The underlying causal agents of this dysfunction are not clear. Ketamine has been used to treat chronic pain in a variety of pain syndromes, including fibromyalgia, but the dosing protocols used are neither standardized nor consistent across cases. The current case presents an opportunity to contribute to a progression towards a consensus on ketamine dosing for fibromyalgia. # Case Presentation A 60-year-old female presented with indications of fibromyalgia and was administered a 9-session IV ketamine treatment for pain. The initial dosing was 50 mg, with a concentration of 1.0 mg/ml at an infusion rate of 0.8 mg/kg/hr. This was increased to 200 mg and eventually to 240 mg, maintaining a ketamine concentration 4.0--4.8 mg/ml at an infusion rate of 1.5 mg/kg/hr. # Management and Outcomes Following the first 9-session therapy, the patient reported \>50% pain relief from pre-infusion levels and was placed on a maintenance regimen in perpetuity. This regimen involves two monthly IV ketamine infusions, one day apart for two hours at a maintenance rate of 4.8 mg/kg/hr. # Conclusion Ketamine by IV is an effective option for pain management in patients with fibromyalgia. Compared to previous case studies, it is recommended that increased total dose, frequent administration, and longer duration of infusions all may be necessary for ketamine to maximize its beneficial effects.
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spelling doaj.art-170cb8bd31a84271aedfd048e4d280d92023-12-30T03:34:03ZengOpen Medical PublishingHealth Psychology Research2420-81242023-11-0111Maintenance IV Ketamine Therapy in the Fibromyalgia Patient: A Case ReportRuchir GuptaSupurna Bhar# Introduction Fibromyalgia is a complex disorder characterized by distributed and persistent pain often associated with fatigue and depression. The underlying causal agents of this dysfunction are not clear. Ketamine has been used to treat chronic pain in a variety of pain syndromes, including fibromyalgia, but the dosing protocols used are neither standardized nor consistent across cases. The current case presents an opportunity to contribute to a progression towards a consensus on ketamine dosing for fibromyalgia. # Case Presentation A 60-year-old female presented with indications of fibromyalgia and was administered a 9-session IV ketamine treatment for pain. The initial dosing was 50 mg, with a concentration of 1.0 mg/ml at an infusion rate of 0.8 mg/kg/hr. This was increased to 200 mg and eventually to 240 mg, maintaining a ketamine concentration 4.0--4.8 mg/ml at an infusion rate of 1.5 mg/kg/hr. # Management and Outcomes Following the first 9-session therapy, the patient reported \>50% pain relief from pre-infusion levels and was placed on a maintenance regimen in perpetuity. This regimen involves two monthly IV ketamine infusions, one day apart for two hours at a maintenance rate of 4.8 mg/kg/hr. # Conclusion Ketamine by IV is an effective option for pain management in patients with fibromyalgia. Compared to previous case studies, it is recommended that increased total dose, frequent administration, and longer duration of infusions all may be necessary for ketamine to maximize its beneficial effects.https://doi.org/10.52965/001c.89640
spellingShingle Ruchir Gupta
Supurna Bhar
Maintenance IV Ketamine Therapy in the Fibromyalgia Patient: A Case Report
Health Psychology Research
title Maintenance IV Ketamine Therapy in the Fibromyalgia Patient: A Case Report
title_full Maintenance IV Ketamine Therapy in the Fibromyalgia Patient: A Case Report
title_fullStr Maintenance IV Ketamine Therapy in the Fibromyalgia Patient: A Case Report
title_full_unstemmed Maintenance IV Ketamine Therapy in the Fibromyalgia Patient: A Case Report
title_short Maintenance IV Ketamine Therapy in the Fibromyalgia Patient: A Case Report
title_sort maintenance iv ketamine therapy in the fibromyalgia patient a case report
url https://doi.org/10.52965/001c.89640
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