Epigenetic signatures of gestational diabetes mellitus on cord blood methylation

Epigenetic signatures of gestational diabetes mellitus on cord blood methylation

Abstract Background Intrauterine exposure to gestational diabetes mellitus (GDM) confers a lifelong increased risk for metabolic and other complex disorders to the offspring. GDM-induced epigenetic modifications modulating gene regulation and persisting into later life are generally assumed to media...

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Bibliographic Details
Main Authors: Larissa Haertle, Nady El Hajj, Marcus Dittrich, Tobias Müller, Indrajit Nanda, Harald Lehnen, Thomas Haaf
Format: Article
Language:English
Published: BMC 2017-03-01
Series:Clinical Epigenetics
Subjects:
DNA methylation
Fetal cord blood
Fetal programming
Gestational diabetes mellitus
Insulin treatment
Online Access:http://link.springer.com/article/10.1186/s13148-017-0329-3

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