A Highly Sensitive Cell-Based TLR Reporter Platform for the Specific Detection of Bacterial TLR Ligands

A Highly Sensitive Cell-Based TLR Reporter Platform for the Specific Detection of Bacterial TLR Ligands

Toll-like receptors (TLRs) are primary pattern recognition receptors (PRRs), which recognize conserved microbial components. They play important roles in innate immunity but also in the initiation of adaptive immune responses. Impurities containing TLR ligands are a frequent problem in research but...

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Bibliographic Details
Main Authors: Katharina Radakovics, Claire Battin, Judith Leitner, Sabine Geiselhart, Wolfgang Paster, Johannes Stöckl, Karin Hoffmann-Sommergruber, Peter Steinberger
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
toll-like receptor
TLR
biosensor
bacterial contamination
reporter cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.817604/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.817604/full

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