Malaria risk stratification in Lao PDR guides program planning in an elimination setting
Abstract Malaria in Lao People’s Democratic Republic (Lao PDR) has declined rapidly over the last two decades, from 279,903 to 3926 (99%) cases between 2001 and 2021. Elimination of human malaria is an achievable goal and limited resources need to be targeted at remaining hotspots of transmission. I...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-01-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-024-52115-2 |
| _version_ | 1797349903422193664 |
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| author | Phoutnalong Vilay Julia C. Dunn Odai Sichanthongthip Rita Reyburn Phonephet Butphomvihane Vilaisak Phiphakavong Punam Amratia Mary Hahm Vilayphone Phongchantha Chitsavang Chanthavisouk Boualam Khamlome Keobouphaphone Chindavongsa Virasack Banouvong Matthew Shortus |
| author_facet | Phoutnalong Vilay Julia C. Dunn Odai Sichanthongthip Rita Reyburn Phonephet Butphomvihane Vilaisak Phiphakavong Punam Amratia Mary Hahm Vilayphone Phongchantha Chitsavang Chanthavisouk Boualam Khamlome Keobouphaphone Chindavongsa Virasack Banouvong Matthew Shortus |
| author_sort | Phoutnalong Vilay |
| collection | DOAJ |
| description | Abstract Malaria in Lao People’s Democratic Republic (Lao PDR) has declined rapidly over the last two decades, from 279,903 to 3926 (99%) cases between 2001 and 2021. Elimination of human malaria is an achievable goal and limited resources need to be targeted at remaining hotspots of transmission. In 2022, the Center of Malariology, Parasitology and Entomology (CMPE) conducted an epidemiological stratification exercise to assign districts and health facility catchment areas (HFCAs) in Lao PDR based on malaria risk. The stratification used reported malaria case numbers from 2019 to 2021, risk maps derived from predictive modelling, and feedback from malaria staff nationwide. Of 148 districts, 14 were deemed as burden reduction (high risk) districts and the remaining 134 as elimination (low risk) districts. Out of 1235 HFCAs, 88 (7%) were classified as highest risk, an improvement from 187 (15%) in the last stratification in 2019. Using the HFCA-level stratification, the updated stratification resulted in the at-risk population (total population in Strata 2, 3 and 4 HFCAs) declining from 3,210,191 to 2,366,068, a 26% decrease. CMPE are using the stratification results to strengthen targeting of resources. Updating national stratifications is a necessary exercise to assess progress in malaria control, reassign interventions to the highest risk populations in the country and ensure greatest impact of limited resources. |
| first_indexed | 2024-03-08T12:37:08Z |
| format | Article |
| id | doaj.art-171aa7bc3fbc472e8a07e6a6955934fc |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-08T12:37:08Z |
| publishDate | 2024-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-171aa7bc3fbc472e8a07e6a6955934fc2024-01-21T12:22:30ZengNature PortfolioScientific Reports2045-23222024-01-0114111210.1038/s41598-024-52115-2Malaria risk stratification in Lao PDR guides program planning in an elimination settingPhoutnalong Vilay0Julia C. Dunn1Odai Sichanthongthip2Rita Reyburn3Phonephet Butphomvihane4Vilaisak Phiphakavong5Punam Amratia6Mary Hahm7Vilayphone Phongchantha8Chitsavang Chanthavisouk9Boualam Khamlome10Keobouphaphone Chindavongsa11Virasack Banouvong12Matthew Shortus13Center of Malariology, Parasitology and EntomologyClinton Health Access InitiativeCenter of Malariology, Parasitology and EntomologyWorld Health OrganizationWorld Health OrganizationWorld Health OrganizationMalaria Atlas Project, Telethon Kids InstituteClinton Health Access InitiativeClinton Health Access InitiativeWorld Health OrganizationCenter of Malariology, Parasitology and EntomologyCenter of Malariology, Parasitology and EntomologyCenter of Malariology, Parasitology and EntomologyWorld Health OrganizationAbstract Malaria in Lao People’s Democratic Republic (Lao PDR) has declined rapidly over the last two decades, from 279,903 to 3926 (99%) cases between 2001 and 2021. Elimination of human malaria is an achievable goal and limited resources need to be targeted at remaining hotspots of transmission. In 2022, the Center of Malariology, Parasitology and Entomology (CMPE) conducted an epidemiological stratification exercise to assign districts and health facility catchment areas (HFCAs) in Lao PDR based on malaria risk. The stratification used reported malaria case numbers from 2019 to 2021, risk maps derived from predictive modelling, and feedback from malaria staff nationwide. Of 148 districts, 14 were deemed as burden reduction (high risk) districts and the remaining 134 as elimination (low risk) districts. Out of 1235 HFCAs, 88 (7%) were classified as highest risk, an improvement from 187 (15%) in the last stratification in 2019. Using the HFCA-level stratification, the updated stratification resulted in the at-risk population (total population in Strata 2, 3 and 4 HFCAs) declining from 3,210,191 to 2,366,068, a 26% decrease. CMPE are using the stratification results to strengthen targeting of resources. Updating national stratifications is a necessary exercise to assess progress in malaria control, reassign interventions to the highest risk populations in the country and ensure greatest impact of limited resources.https://doi.org/10.1038/s41598-024-52115-2 |
| spellingShingle | Phoutnalong Vilay Julia C. Dunn Odai Sichanthongthip Rita Reyburn Phonephet Butphomvihane Vilaisak Phiphakavong Punam Amratia Mary Hahm Vilayphone Phongchantha Chitsavang Chanthavisouk Boualam Khamlome Keobouphaphone Chindavongsa Virasack Banouvong Matthew Shortus Malaria risk stratification in Lao PDR guides program planning in an elimination setting Scientific Reports |
| title | Malaria risk stratification in Lao PDR guides program planning in an elimination setting |
| title_full | Malaria risk stratification in Lao PDR guides program planning in an elimination setting |
| title_fullStr | Malaria risk stratification in Lao PDR guides program planning in an elimination setting |
| title_full_unstemmed | Malaria risk stratification in Lao PDR guides program planning in an elimination setting |
| title_short | Malaria risk stratification in Lao PDR guides program planning in an elimination setting |
| title_sort | malaria risk stratification in lao pdr guides program planning in an elimination setting |
| url | https://doi.org/10.1038/s41598-024-52115-2 |
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