Genome-wide RNAi Screen Identifies Networks Involved in Intestinal Stem Cell Regulation in Drosophila

The intestinal epithelium is the most rapidly self-renewing tissue in adult animals and maintained by intestinal stem cells (ISCs) in both Drosophila and mammals. To comprehensively identify genes and pathways that regulate ISC fates, we performed a genome-wide transgenic RNAi screen in adult Drosop...

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Bibliographic Details
Main Authors: Xiankun Zeng, Lili Han, Shree Ram Singh, Hanhan Liu, Ralph A. Neumüller, Dong Yan, Yanhui Hu, Ying Liu, Wei Liu, Xinhua Lin, Steven X. Hou
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715000765